MiR-199-3p enhances muscle regeneration and ameliorates aged muscle and muscular dystrophy

Fukuoka et al. investigate the possible role of miR-199-3p during aging, which significantly decreases in the blood of aged mice compared to young mice. They also show that miR-199-3p enhance muscle regeneration, and administering miR-199 mimics to mdx mice, a dystrophy animal model, markedly improv...

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Autores principales:	Masashi Fukuoka, Hiromi Fujita, Kosumo Numao, Yasuko Nakamura, Hideo Shimizu, Masayuki Sekiguchi, Hirohiko Hohjoh
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/8bbe8e8563d9448996b481d9af3377be
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spelling	oai:doaj.org-article:8bbe8e8563d9448996b481d9af3377be2021-12-02T18:17:53ZMiR-199-3p enhances muscle regeneration and ameliorates aged muscle and muscular dystrophy10.1038/s42003-021-01952-22399-3642https://doaj.org/article/8bbe8e8563d9448996b481d9af3377be2021-03-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-01952-2https://doaj.org/toc/2399-3642Fukuoka et al. investigate the possible role of miR-199-3p during aging, which significantly decreases in the blood of aged mice compared to young mice. They also show that miR-199-3p enhance muscle regeneration, and administering miR-199 mimics to mdx mice, a dystrophy animal model, markedly improves muscle strength of the mice, highlighting its therapeutic potential.Masashi FukuokaHiromi FujitaKosumo NumaoYasuko NakamuraHideo ShimizuMasayuki SekiguchiHirohiko HohjohNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-12 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 Masashi Fukuoka Hiromi Fujita Kosumo Numao Yasuko Nakamura Hideo Shimizu Masayuki Sekiguchi Hirohiko Hohjoh MiR-199-3p enhances muscle regeneration and ameliorates aged muscle and muscular dystrophy
description	Fukuoka et al. investigate the possible role of miR-199-3p during aging, which significantly decreases in the blood of aged mice compared to young mice. They also show that miR-199-3p enhance muscle regeneration, and administering miR-199 mimics to mdx mice, a dystrophy animal model, markedly improves muscle strength of the mice, highlighting its therapeutic potential.
format	article
author	Masashi Fukuoka Hiromi Fujita Kosumo Numao Yasuko Nakamura Hideo Shimizu Masayuki Sekiguchi Hirohiko Hohjoh
author_facet	Masashi Fukuoka Hiromi Fujita Kosumo Numao Yasuko Nakamura Hideo Shimizu Masayuki Sekiguchi Hirohiko Hohjoh
author_sort	Masashi Fukuoka
title	MiR-199-3p enhances muscle regeneration and ameliorates aged muscle and muscular dystrophy
title_short	MiR-199-3p enhances muscle regeneration and ameliorates aged muscle and muscular dystrophy
title_full	MiR-199-3p enhances muscle regeneration and ameliorates aged muscle and muscular dystrophy
title_fullStr	MiR-199-3p enhances muscle regeneration and ameliorates aged muscle and muscular dystrophy
title_full_unstemmed	MiR-199-3p enhances muscle regeneration and ameliorates aged muscle and muscular dystrophy
title_sort	mir-199-3p enhances muscle regeneration and ameliorates aged muscle and muscular dystrophy
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/8bbe8e8563d9448996b481d9af3377be
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MiR-199-3p enhances muscle regeneration and ameliorates aged muscle and muscular dystrophy

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