Accurate and rapid estimation of phosphene thresholds (REPT).

To calibrate the intensity of transcranial magnetic stimulation (TMS) at the occipital pole, the phosphene threshold is used as a measure of cortical excitability. The phosphene threshold (PT) refers to the intensity of magnetic stimulation that induces illusory flashes of light (phosphenes) on a pr...

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Autores principales:	Arman Abrahamyan, Colin W G Clifford, Manuela Ruzzoli, Dan Phillips, Ehsan Arabzadeh, Justin A Harris
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2011
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/8bc7a66a3b4b4449a7edc8c68b8a01e2
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spelling	oai:doaj.org-article:8bc7a66a3b4b4449a7edc8c68b8a01e22021-11-18T06:49:37ZAccurate and rapid estimation of phosphene thresholds (REPT).1932-620310.1371/journal.pone.0022342https://doaj.org/article/8bc7a66a3b4b4449a7edc8c68b8a01e22011-01-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21799833/pdf/?tool=EBIhttps://doaj.org/toc/1932-6203To calibrate the intensity of transcranial magnetic stimulation (TMS) at the occipital pole, the phosphene threshold is used as a measure of cortical excitability. The phosphene threshold (PT) refers to the intensity of magnetic stimulation that induces illusory flashes of light (phosphenes) on a proportion of trials. The existing PT estimation procedures lack the accuracy and mathematical rigour of modern threshold estimation methods. We present an improved and automatic procedure for estimating the PT which is based on the well-established Ψ Bayesian adaptive staircase approach. To validate the new procedure, we compared it with another commonly used procedure for estimating the PT. We found that our procedure is more accurate, reliable, and rapid when compared with an existing PT measurement procedure. The new procedure is implemented in Matlab and works automatically with the Magstim Rapid(2) stimulator using a convenient graphical user interface. The Matlab program is freely available for download.Arman AbrahamyanColin W G CliffordManuela RuzzoliDan PhillipsEhsan ArabzadehJustin A HarrisPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 6, Iss 7, p e22342 (2011)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Arman Abrahamyan Colin W G Clifford Manuela Ruzzoli Dan Phillips Ehsan Arabzadeh Justin A Harris Accurate and rapid estimation of phosphene thresholds (REPT).
description	To calibrate the intensity of transcranial magnetic stimulation (TMS) at the occipital pole, the phosphene threshold is used as a measure of cortical excitability. The phosphene threshold (PT) refers to the intensity of magnetic stimulation that induces illusory flashes of light (phosphenes) on a proportion of trials. The existing PT estimation procedures lack the accuracy and mathematical rigour of modern threshold estimation methods. We present an improved and automatic procedure for estimating the PT which is based on the well-established Ψ Bayesian adaptive staircase approach. To validate the new procedure, we compared it with another commonly used procedure for estimating the PT. We found that our procedure is more accurate, reliable, and rapid when compared with an existing PT measurement procedure. The new procedure is implemented in Matlab and works automatically with the Magstim Rapid(2) stimulator using a convenient graphical user interface. The Matlab program is freely available for download.
format	article
author	Arman Abrahamyan Colin W G Clifford Manuela Ruzzoli Dan Phillips Ehsan Arabzadeh Justin A Harris
author_facet	Arman Abrahamyan Colin W G Clifford Manuela Ruzzoli Dan Phillips Ehsan Arabzadeh Justin A Harris
author_sort	Arman Abrahamyan
title	Accurate and rapid estimation of phosphene thresholds (REPT).
title_short	Accurate and rapid estimation of phosphene thresholds (REPT).
title_full	Accurate and rapid estimation of phosphene thresholds (REPT).
title_fullStr	Accurate and rapid estimation of phosphene thresholds (REPT).
title_full_unstemmed	Accurate and rapid estimation of phosphene thresholds (REPT).
title_sort	accurate and rapid estimation of phosphene thresholds (rept).
publisher	Public Library of Science (PLoS)
publishDate	2011
url	https://doaj.org/article/8bc7a66a3b4b4449a7edc8c68b8a01e2
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Accurate and rapid estimation of phosphene thresholds (REPT).

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