Extensive Gene Amplification as a Mechanism for Piperacillin-Tazobactam Resistance in <named-content content-type="genus-species">Escherichia coli</named-content>
ABSTRACT Although the TEM-1 β-lactamase (BlaTEM-1) hydrolyzes penicillins and narrow-spectrum cephalosporins, organisms expressing this enzyme are typically susceptible to β-lactam/β-lactamase inhibitor combinations such as piperacillin-tazobactam (TZP). However, our previous work led to the discove...
Saved in:
Main Authors: | Lisa M. Schechter, David P. Creely, Cherilyn D. Garner, Dee Shortridge, Hoan Nguyen, Lei Chen, Blake M. Hanson, Erica Sodergren, George M. Weinstock, W. Michael Dunne, Alex van Belkum, Shana R. Leopold |
---|---|
Format: | article |
Language: | EN |
Published: |
American Society for Microbiology
2018
|
Subjects: | |
Online Access: | https://doaj.org/article/8bc875ddf68a47e3b51e256a2aab5b35 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
SIMULTANEOUS DETERMINATION OF PIPERACILLIN AND TAZOBACTAM IN THE PHARMACEUTICAL FORMULATION TAZONAM® BY DERIVATIVE SPECTROPHOTOMETRY
by: TORAL,M. INÉS, et al.
Published: (2012) -
Pharmacokinetics and outcome of tazobactam/piperacillin in Japanese patients undergoing low-flow continuous renal replacement therapy: dosage considerations
by: Kohama H, et al.
Published: (2017) -
Susceptibilidad de enterobacterias a piperacilina/tazobactam en un hospital pediátrico de Chile
by: Vega,Juan Rojas De la, et al.
Published: (2017) -
Ceftolozane-tazobactam activity against clinical isolates of Pseudomonas aeruginosa from ICU patients with pneumonia: United States, 2015–2018
by: Michael A. Pfaller, et al.
Published: (2021) -
Concentraciones plasmáticas de piperacilina/tazobactam en pacientes pediátricos críticos sometidos a ECMO. Análisis preliminar
by: Zylbersztajn,Brenda, et al.
Published: (2020)