Mfsd2a+ hepatocytes repopulate the liver during injury and regeneration

Hepatocytes are highly specialized cells and their fate is determined by their position in the liver as either periportal or perivenous hepatocytes. Here, Pu et al. show through genetic lineage tracing for Mfsd2 that periportal hepatocytes proliferate and reprogram into pericentral hepatocytes durin...

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Autores principales:	Wenjuan Pu, Hui Zhang, Xiuzhen Huang, Xueying Tian, Lingjuan He, Yue Wang, Libo Zhang, Qiaozhen Liu, Yan Li, Yi Li, Huan Zhao, Kuo Liu, Jie Lu, Yingqun Zhou, Pengyu Huang, Yu Nie, Yan Yan, Lijian Hui, Kathy O. Lui, Bin Zhou
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/8bcbb5f141f84e2ebd07ff6d5e9adba5
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spelling	oai:doaj.org-article:8bcbb5f141f84e2ebd07ff6d5e9adba52021-12-02T16:49:57ZMfsd2a+ hepatocytes repopulate the liver during injury and regeneration10.1038/ncomms133692041-1723https://doaj.org/article/8bcbb5f141f84e2ebd07ff6d5e9adba52016-11-01T00:00:00Zhttps://doi.org/10.1038/ncomms13369https://doaj.org/toc/2041-1723Hepatocytes are highly specialized cells and their fate is determined by their position in the liver as either periportal or perivenous hepatocytes. Here, Pu et al. show through genetic lineage tracing for Mfsd2 that periportal hepatocytes proliferate and reprogram into pericentral hepatocytes during liver regeneration and injury.Wenjuan PuHui ZhangXiuzhen HuangXueying TianLingjuan HeYue WangLibo ZhangQiaozhen LiuYan LiYi LiHuan ZhaoKuo LiuJie LuYingqun ZhouPengyu HuangYu NieYan YanLijian HuiKathy O. LuiBin ZhouNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-15 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Wenjuan Pu Hui Zhang Xiuzhen Huang Xueying Tian Lingjuan He Yue Wang Libo Zhang Qiaozhen Liu Yan Li Yi Li Huan Zhao Kuo Liu Jie Lu Yingqun Zhou Pengyu Huang Yu Nie Yan Yan Lijian Hui Kathy O. Lui Bin Zhou Mfsd2a+ hepatocytes repopulate the liver during injury and regeneration
description	Hepatocytes are highly specialized cells and their fate is determined by their position in the liver as either periportal or perivenous hepatocytes. Here, Pu et al. show through genetic lineage tracing for Mfsd2 that periportal hepatocytes proliferate and reprogram into pericentral hepatocytes during liver regeneration and injury.
format	article
author	Wenjuan Pu Hui Zhang Xiuzhen Huang Xueying Tian Lingjuan He Yue Wang Libo Zhang Qiaozhen Liu Yan Li Yi Li Huan Zhao Kuo Liu Jie Lu Yingqun Zhou Pengyu Huang Yu Nie Yan Yan Lijian Hui Kathy O. Lui Bin Zhou
author_facet	Wenjuan Pu Hui Zhang Xiuzhen Huang Xueying Tian Lingjuan He Yue Wang Libo Zhang Qiaozhen Liu Yan Li Yi Li Huan Zhao Kuo Liu Jie Lu Yingqun Zhou Pengyu Huang Yu Nie Yan Yan Lijian Hui Kathy O. Lui Bin Zhou
author_sort	Wenjuan Pu
title	Mfsd2a+ hepatocytes repopulate the liver during injury and regeneration
title_short	Mfsd2a+ hepatocytes repopulate the liver during injury and regeneration
title_full	Mfsd2a+ hepatocytes repopulate the liver during injury and regeneration
title_fullStr	Mfsd2a+ hepatocytes repopulate the liver during injury and regeneration
title_full_unstemmed	Mfsd2a+ hepatocytes repopulate the liver during injury and regeneration
title_sort	mfsd2a+ hepatocytes repopulate the liver during injury and regeneration
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/8bcbb5f141f84e2ebd07ff6d5e9adba5
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Mfsd2a+ hepatocytes repopulate the liver during injury and regeneration

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