Epidemiology of multidrug-resistant microorganisms among nursing home residents in Belgium.

<h4>Objectives</h4>A national survey was conducted to determine the prevalence and risk factors of methicillin-resistant Staphylococcus aureus (MRSA), extended-spectrum β-lactamases-producing Enterobacteriaceae (ESBLE) and vancomycin-resistant enterococci (VRE) among nursing home residen...

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Autores principales:	Béatrice Jans, Didier Schoevaerdts, Te-Din Huang, Catherine Berhin, Katrien Latour, Pierre Bogaerts, Claire Nonhoff, Olivier Denis, Boudewijn Catry, Youri Glupczynski
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2013
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/8be51bb455594ded91d7c43965816684
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spelling	oai:doaj.org-article:8be51bb455594ded91d7c439658166842021-11-18T07:43:43ZEpidemiology of multidrug-resistant microorganisms among nursing home residents in Belgium.1932-620310.1371/journal.pone.0064908https://doaj.org/article/8be51bb455594ded91d7c439658166842013-01-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23738011/?tool=EBIhttps://doaj.org/toc/1932-6203<h4>Objectives</h4>A national survey was conducted to determine the prevalence and risk factors of methicillin-resistant Staphylococcus aureus (MRSA), extended-spectrum β-lactamases-producing Enterobacteriaceae (ESBLE) and vancomycin-resistant enterococci (VRE) among nursing home residents in Belgium.<h4>Methods</h4>A random stratified, national prevalence survey was conducted in nursing home residents who were screened for carriage of ESBLE, MRSA and VRE by multisite enriched culture. Characteristics of nursing homes and residents were collected by a questionnaire survey and were analysed by multilevel logistic regression analysis.<h4>Results</h4>Of 2791 screened residents in 60 participating nursing home, the weighted prevalence of ESBLE and MRSA carriage were 6.2% (range: 0 to 20%) and 12.2% (range: 0 to 36%), respectively. No cases of VRE were found. No relationship was found between ESBLE and MRSA prevalence rates within nursing homes and the rate of co-colonization was very low (0.8%). Geographical variations in prevalence of MRSA and ESBLE and in distribution of ESBL types in nursing home residents paralleled that of acute hospitals. Risk factors of ESBLE carriage included previously known ESBLE carriage, male gender, a low level of mobility and previous antibiotic exposure. Risk factors for MRSA colonization were: previously known MRSA carriage, skin lesions, a low functional status and antacid use.<h4>Conclusions</h4>A low prevalence of ESBLE carriage was found in nursing home residents in Belgium. The prevalence of MRSA carriage decreased substantially in comparison to a similar survey conducted in 2005. A low functional status appeared as a common factor for ESBLE and MRSA carriage. Previous exposure to antibiotics was a strong predictor of ESBLE colonization while increased clustering of MRSA carriage suggested the importance of cross-transmission within nursing homes for this organism. These results emphasize the need for global coordination of the surveillance of MDRO within and between nursing homes and hospitals.Béatrice JansDidier SchoevaerdtsTe-Din HuangCatherine BerhinKatrien LatourPierre BogaertsClaire NonhoffOlivier DenisBoudewijn CatryYouri GlupczynskiPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 8, Iss 5, p e64908 (2013)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Béatrice Jans Didier Schoevaerdts Te-Din Huang Catherine Berhin Katrien Latour Pierre Bogaerts Claire Nonhoff Olivier Denis Boudewijn Catry Youri Glupczynski Epidemiology of multidrug-resistant microorganisms among nursing home residents in Belgium.
description	<h4>Objectives</h4>A national survey was conducted to determine the prevalence and risk factors of methicillin-resistant Staphylococcus aureus (MRSA), extended-spectrum β-lactamases-producing Enterobacteriaceae (ESBLE) and vancomycin-resistant enterococci (VRE) among nursing home residents in Belgium.<h4>Methods</h4>A random stratified, national prevalence survey was conducted in nursing home residents who were screened for carriage of ESBLE, MRSA and VRE by multisite enriched culture. Characteristics of nursing homes and residents were collected by a questionnaire survey and were analysed by multilevel logistic regression analysis.<h4>Results</h4>Of 2791 screened residents in 60 participating nursing home, the weighted prevalence of ESBLE and MRSA carriage were 6.2% (range: 0 to 20%) and 12.2% (range: 0 to 36%), respectively. No cases of VRE were found. No relationship was found between ESBLE and MRSA prevalence rates within nursing homes and the rate of co-colonization was very low (0.8%). Geographical variations in prevalence of MRSA and ESBLE and in distribution of ESBL types in nursing home residents paralleled that of acute hospitals. Risk factors of ESBLE carriage included previously known ESBLE carriage, male gender, a low level of mobility and previous antibiotic exposure. Risk factors for MRSA colonization were: previously known MRSA carriage, skin lesions, a low functional status and antacid use.<h4>Conclusions</h4>A low prevalence of ESBLE carriage was found in nursing home residents in Belgium. The prevalence of MRSA carriage decreased substantially in comparison to a similar survey conducted in 2005. A low functional status appeared as a common factor for ESBLE and MRSA carriage. Previous exposure to antibiotics was a strong predictor of ESBLE colonization while increased clustering of MRSA carriage suggested the importance of cross-transmission within nursing homes for this organism. These results emphasize the need for global coordination of the surveillance of MDRO within and between nursing homes and hospitals.
format	article
author	Béatrice Jans Didier Schoevaerdts Te-Din Huang Catherine Berhin Katrien Latour Pierre Bogaerts Claire Nonhoff Olivier Denis Boudewijn Catry Youri Glupczynski
author_facet	Béatrice Jans Didier Schoevaerdts Te-Din Huang Catherine Berhin Katrien Latour Pierre Bogaerts Claire Nonhoff Olivier Denis Boudewijn Catry Youri Glupczynski
author_sort	Béatrice Jans
title	Epidemiology of multidrug-resistant microorganisms among nursing home residents in Belgium.
title_short	Epidemiology of multidrug-resistant microorganisms among nursing home residents in Belgium.
title_full	Epidemiology of multidrug-resistant microorganisms among nursing home residents in Belgium.
title_fullStr	Epidemiology of multidrug-resistant microorganisms among nursing home residents in Belgium.
title_full_unstemmed	Epidemiology of multidrug-resistant microorganisms among nursing home residents in Belgium.
title_sort	epidemiology of multidrug-resistant microorganisms among nursing home residents in belgium.
publisher	Public Library of Science (PLoS)
publishDate	2013
url	https://doaj.org/article/8be51bb455594ded91d7c43965816684
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Epidemiology of multidrug-resistant microorganisms among nursing home residents in Belgium.

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