Low-dose aripiprazole for refractory burning mouth syndrome

Low-dose aripiprazole for refractory burning mouth syndrome

Yojiro Umezaki,1 Miho Takenoshita,2 Akira Toyofuku2 1Psychosomatic Dentistry Clinic, Dental Hospital, 2Psychosomatic Dentistry, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan Abstract: We report a case of refractory burning mouth syndrome (BMS) am...

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Autores principales: Umezaki Y, Takenoshita M, Toyofuku A
Formato: article
Lenguaje:EN
Publicado: Dove Medical Press 2016
Materias:
Burning mouth syndrome
low dose aripiprazole
chronic pain
Neurosciences. Biological psychiatry. Neuropsychiatry
RC321-571
Neurology. Diseases of the nervous system
RC346-429
Acceso en línea:https://doaj.org/article/8be633c22e254f82979b65f440de9cb5
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spelling oai:doaj.org-article:8be633c22e254f82979b65f440de9cb52021-12-02T07:30:55ZLow-dose aripiprazole for refractory burning mouth syndrome1178-2021https://doaj.org/article/8be633c22e254f82979b65f440de9cb52016-05-01T00:00:00Zhttps://www.dovepress.com/low-dose-aripiprazole-for-refractory-burning-mouth-syndrome-peer-reviewed-article-NDThttps://doaj.org/toc/1178-2021Yojiro Umezaki,1 Miho Takenoshita,2 Akira Toyofuku2 1Psychosomatic Dentistry Clinic, Dental Hospital, 2Psychosomatic Dentistry, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan Abstract: We report a case of refractory burning mouth syndrome (BMS) ameliorated with low dose of aripiprazole. The patient was a 66-year-old female who had suffered from chronic burning pain in her tongue for 13 months. No abnormality associated with the burning sensation was detected in the laboratory tests and the oral findings. Considering the clinical feature and the history together, we diagnosed the burning sensation as BMS. The BMS pain was decreased by aripiprazole (powder) 1.0 mg/d, though no other antidepressants had satisfying pain relief. It could be supposed that the efficacy of aripiprazole is caused by dopamine stabilization in this case, and BMS might have a subtype that is reactive to aripiprazole. Further studies are needed to confirm the efficacy of aripiprazole for BMS. Keywords: burning mouth syndrome, low-dose aripiprazole, chronic painUmezaki YTakenoshita MToyofuku ADove Medical PressarticleBurning mouth syndromelow dose aripiprazolechronic painNeurosciences. Biological psychiatry. NeuropsychiatryRC321-571Neurology. Diseases of the nervous systemRC346-429ENNeuropsychiatric Disease and Treatment, Vol 2016, Iss Issue 1, Pp 1229-1231 (2016)
institution DOAJ
collection DOAJ
language EN
topic Burning mouth syndrome
low dose aripiprazole
chronic pain
Neurosciences. Biological psychiatry. Neuropsychiatry
RC321-571
Neurology. Diseases of the nervous system
RC346-429
spellingShingle Burning mouth syndrome
low dose aripiprazole
chronic pain
Neurosciences. Biological psychiatry. Neuropsychiatry
RC321-571
Neurology. Diseases of the nervous system
RC346-429
Umezaki Y
Takenoshita M
Toyofuku A
Low-dose aripiprazole for refractory burning mouth syndrome
description Yojiro Umezaki,1 Miho Takenoshita,2 Akira Toyofuku2 1Psychosomatic Dentistry Clinic, Dental Hospital, 2Psychosomatic Dentistry, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan Abstract: We report a case of refractory burning mouth syndrome (BMS) ameliorated with low dose of aripiprazole. The patient was a 66-year-old female who had suffered from chronic burning pain in her tongue for 13 months. No abnormality associated with the burning sensation was detected in the laboratory tests and the oral findings. Considering the clinical feature and the history together, we diagnosed the burning sensation as BMS. The BMS pain was decreased by aripiprazole (powder) 1.0 mg/d, though no other antidepressants had satisfying pain relief. It could be supposed that the efficacy of aripiprazole is caused by dopamine stabilization in this case, and BMS might have a subtype that is reactive to aripiprazole. Further studies are needed to confirm the efficacy of aripiprazole for BMS. Keywords: burning mouth syndrome, low-dose aripiprazole, chronic pain
format article
author Umezaki Y
Takenoshita M
Toyofuku A
author_facet Umezaki Y
Takenoshita M
Toyofuku A
author_sort Umezaki Y
title Low-dose aripiprazole for refractory burning mouth syndrome
title_short Low-dose aripiprazole for refractory burning mouth syndrome
title_full Low-dose aripiprazole for refractory burning mouth syndrome
title_fullStr Low-dose aripiprazole for refractory burning mouth syndrome
title_full_unstemmed Low-dose aripiprazole for refractory burning mouth syndrome
title_sort low-dose aripiprazole for refractory burning mouth syndrome
publisher Dove Medical Press
publishDate 2016
url https://doaj.org/article/8be633c22e254f82979b65f440de9cb5
work_keys_str_mv AT umezakiy lowdosearipiprazoleforrefractoryburningmouthsyndrome
AT takenoshitam lowdosearipiprazoleforrefractoryburningmouthsyndrome
AT toyofukua lowdosearipiprazoleforrefractoryburningmouthsyndrome
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