The calcium sensor Copine-6 regulates spine structural plasticity and learning and memory
Learning and memory depend on the structural and functional plasticity of synapses. Reinhard et al. show that the calcium sensor Copine-6 is required for memory, controls spine structure by regulating Rac signalling, and through its modulation of actin, supports hippocampal LTP.
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Autores principales: | , , , , , , |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2016
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Materias: | |
Acceso en línea: | https://doaj.org/article/8bea66530dd040039859aae13ab08ebc |
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Sumario: | Learning and memory depend on the structural and functional plasticity of synapses. Reinhard et al. show that the calcium sensor Copine-6 is required for memory, controls spine structure by regulating Rac signalling, and through its modulation of actin, supports hippocampal LTP. |
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