The calcium sensor Copine-6 regulates spine structural plasticity and learning and memory

Learning and memory depend on the structural and functional plasticity of synapses. Reinhard et al. show that the calcium sensor Copine-6 is required for memory, controls spine structure by regulating Rac signalling, and through its modulation of actin, supports hippocampal LTP.

Guardado en:

Detalles Bibliográficos
Autores principales:	Judith R. Reinhard, Alexander Kriz, Milos Galic, Nico Angliker, Mathieu Rajalu, Kaspar E. Vogt, Markus A. Ruegg
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/8bea66530dd040039859aae13ab08ebc
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:8bea66530dd040039859aae13ab08ebc
record_format	dspace
spelling	oai:doaj.org-article:8bea66530dd040039859aae13ab08ebc2021-12-02T15:35:22ZThe calcium sensor Copine-6 regulates spine structural plasticity and learning and memory10.1038/ncomms116132041-1723https://doaj.org/article/8bea66530dd040039859aae13ab08ebc2016-05-01T00:00:00Zhttps://doi.org/10.1038/ncomms11613https://doaj.org/toc/2041-1723Learning and memory depend on the structural and functional plasticity of synapses. Reinhard et al. show that the calcium sensor Copine-6 is required for memory, controls spine structure by regulating Rac signalling, and through its modulation of actin, supports hippocampal LTP.Judith R. ReinhardAlexander KrizMilos GalicNico AnglikerMathieu RajaluKaspar E. VogtMarkus A. RueggNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Judith R. Reinhard Alexander Kriz Milos Galic Nico Angliker Mathieu Rajalu Kaspar E. Vogt Markus A. Ruegg The calcium sensor Copine-6 regulates spine structural plasticity and learning and memory
description	Learning and memory depend on the structural and functional plasticity of synapses. Reinhard et al. show that the calcium sensor Copine-6 is required for memory, controls spine structure by regulating Rac signalling, and through its modulation of actin, supports hippocampal LTP.
format	article
author	Judith R. Reinhard Alexander Kriz Milos Galic Nico Angliker Mathieu Rajalu Kaspar E. Vogt Markus A. Ruegg
author_facet	Judith R. Reinhard Alexander Kriz Milos Galic Nico Angliker Mathieu Rajalu Kaspar E. Vogt Markus A. Ruegg
author_sort	Judith R. Reinhard
title	The calcium sensor Copine-6 regulates spine structural plasticity and learning and memory
title_short	The calcium sensor Copine-6 regulates spine structural plasticity and learning and memory
title_full	The calcium sensor Copine-6 regulates spine structural plasticity and learning and memory
title_fullStr	The calcium sensor Copine-6 regulates spine structural plasticity and learning and memory
title_full_unstemmed	The calcium sensor Copine-6 regulates spine structural plasticity and learning and memory
title_sort	calcium sensor copine-6 regulates spine structural plasticity and learning and memory
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/8bea66530dd040039859aae13ab08ebc
work_keys_str_mv	AT judithrreinhard thecalciumsensorcopine6regulatesspinestructuralplasticityandlearningandmemory AT alexanderkriz thecalciumsensorcopine6regulatesspinestructuralplasticityandlearningandmemory AT milosgalic thecalciumsensorcopine6regulatesspinestructuralplasticityandlearningandmemory AT nicoangliker thecalciumsensorcopine6regulatesspinestructuralplasticityandlearningandmemory AT mathieurajalu thecalciumsensorcopine6regulatesspinestructuralplasticityandlearningandmemory AT kasparevogt thecalciumsensorcopine6regulatesspinestructuralplasticityandlearningandmemory AT markusaruegg thecalciumsensorcopine6regulatesspinestructuralplasticityandlearningandmemory AT judithrreinhard calciumsensorcopine6regulatesspinestructuralplasticityandlearningandmemory AT alexanderkriz calciumsensorcopine6regulatesspinestructuralplasticityandlearningandmemory AT milosgalic calciumsensorcopine6regulatesspinestructuralplasticityandlearningandmemory AT nicoangliker calciumsensorcopine6regulatesspinestructuralplasticityandlearningandmemory AT mathieurajalu calciumsensorcopine6regulatesspinestructuralplasticityandlearningandmemory AT kasparevogt calciumsensorcopine6regulatesspinestructuralplasticityandlearningandmemory AT markusaruegg calciumsensorcopine6regulatesspinestructuralplasticityandlearningandmemory
_version_	1718386609740578816

The calcium sensor Copine-6 regulates spine structural plasticity and learning and memory

Ejemplares similares