Polyphosphate Functions <italic toggle="yes">In Vivo</italic> as an Iron Chelator and Fenton Reaction Inhibitor

ABSTRACT Maintaining cellular iron homeostasis is critical for organismal survival. Whereas iron depletion negatively affects the many metabolic pathways that depend on the activity of iron-containing enzymes, any excess of iron can cause the rapid formation of highly toxic reactive oxygen species (...

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Autores principales: François Beaufay, Ellen Quarles, Allison Franz, Olivia Katamanin, Wei-Yun Wholey, Ursula Jakob
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2020
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Acceso en línea:https://doaj.org/article/8bf01c8de1334955bd33759e52457c27
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