A novel protein AXIN1-295aa encoded by circAXIN1 activates the Wnt/β-catenin signaling pathway to promote gastric cancer progression
Abstract Background Circular RNA (circRNA), a subclass of non-coding RNA, plays a critical role in cancer tumorigenesis and metastasis. It has been suggested that circRNA acts as a microRNA sponge or a scaffold to interact with protein complexes; however, its full range of functions remains elusive....
Enregistré dans:
Auteurs principaux: | Yin Peng, Yidan Xu, Xiaojing Zhang, Shiqi Deng, Yuan Yuan, Xiaonuan Luo, Md Tofazzal Hossain, Xiaohui Zhu, Kaining Du, Fan Hu, Yang Chen, Shanshan Chang, Xianling Feng, Xinmin Fan, Hassan Ashktorab, Duane Smoot, Stephen J. Meltzer, Gangqiang Hou, Yanjie Wei, Song Li, Ying Qin, Zhe Jin |
---|---|
Format: | article |
Langue: | EN |
Publié: |
BMC
2021
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/8c037b1b95034b6294d7f4a5465b9ed9 |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
Evaluation of AXIN1 and AXIN2 as targets of tankyrase inhibition in hepatocellular carcinoma cell lines
par: Wenhui Wang, et autres
Publié: (2021) -
RESONANCIA MAGNETICA CEREBRAL EN DAÑO AXONAL DIFUSO
par: Mujica B,Máximo, et autres
Publié: (2003) -
USP7 inhibits Wnt/β-catenin signaling through promoting stabilization of Axin
par: Lei Ji, et autres
Publié: (2019) -
Starvation induced autophagy promotes the progression of bladder cancer by LDHA mediated metabolic reprogramming
par: Tinghao Li, et autres
Publié: (2021) -
An aggregon in conductin/axin2 regulates Wnt/β-catenin signaling and holds potential for cancer therapy
par: Dominic B. Bernkopf, et autres
Publié: (2019)