Safinamide: an add-on treatment for managing Parkinson’s disease

Código QR

Safinamide: an add-on treatment for managing Parkinson’s disease

Thomas Müller Department of Neurology, St. Joseph Hospital Berlin-Weißensee, Berlin, Germany Abstract: Heterogeneous expression of neurotransmitter deficits results from onset and progression of Parkinson’s disease. Intervals, characterized by reappearance of motor and a...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autor principal:	Müller T
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2018
Materias:	Safinamide MAO-B inhibition abnormal glutamate release inhibition Parkinson’s disease dopamine substitution glutamate Therapeutics. Pharmacology RM1-950
Acceso en línea:	https://doaj.org/article/8c06556cab854d36b3a3812b7e6f2ccc
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares

Is There a Glutathione Centered Redox Dysregulation Subtype of Schizophrenia?
por: Lena Palaniyappan, et al.
Publicado: (2021)

Osthole inhibits proliferation and induces apoptosis in BV-2 microglia cells in kainic acid-induced epilepsy via modulating PI3K/AKt/mTOR signalling way
por: Meng Du, et al.
Publicado: (2019)

<i>Thunbergia laurifolia</i> Leaf Extract Inhibits Glutamate-Induced Neurotoxicity and Cell Death through Mitophagy Signaling
por: Wudtipong Vongthip, et al.
Publicado: (2021)

The dorsal hippocampal protein targeting to glycogen maintains ionotropic glutamate receptor subunits expression and contributes to working and short-term memories in mice
por: Yuki Kambe, et al.
Publicado: (2022)

A Novel Use of Allopurinol as A Quorum-Sensing Inhibitor in <i>Pseudomonas aeruginosa</i>
por: Ahmed Al Saqr, et al.
Publicado: (2021)

Vitamin D Pretreatment Attenuates Ciprofloxacin-Induced Antibacterial Activity
por: Masadeh MM, et al.
Publicado: (2020)

Pharmacological methods of therapy in Parkinson’s disease
por: Y. N. Bykov, et al.
Publicado: (2016)

A review of ropinirole prolonged release in Parkinson’s disease
por: Muhammad M Nashatizadeh, et al.
Publicado: (2009)

Glutamatergic medications as adjunctive therapy for moderate to severe obsessive-compulsive disorder in adults: a systematic review and meta-analysis
por: Fatemeh Hadi, et al.
Publicado: (2021)

Examination the antioxidant potentials and antidiabetic properties of phenolic extracts of some Iranian honeys
por: Mahmoodreza Moein, et al.
Publicado: (2022)

Exploring the Chemical Profiles and Biological Values of Two <i>Spondias</i> Species (<i>S. dulcis</i> and <i>S. mombin</i>): Valuable Sources of Bioactive Natural Products
por: Kouadio Ibrahime Sinan, et al.
Publicado: (2021)

Phenolic Analysis and In Vitro Biological Activity of Red Wine, Pomace and Grape Seeds Oil Derived from <i>Vitis vinifera</i> L. cv. Montepulciano d’Abruzzo
por: Adriano Mollica, et al.
Publicado: (2021)

mGlu1 potentiation enhances prelimbic somatostatin interneuron activity to rescue schizophrenia-like physiological and cognitive deficits
por: James Maksymetz, et al.
Publicado: (2021)

Activation of group II metabotropic glutamate receptors blocks zinc release from hippocampal mossy fibers
por: Matias,Carlos M, et al.
Publicado: (2014)

Neutrophil NET Formation with Microbial Stimuli Requires Late Stage NADPH Oxidase Activity
por: Heather A. Parker, et al.
Publicado: (2021)

Parkinson’s Disease: Carbidopa, Nausea, and Dyskinesia [Retraction]
por: Hinz M, et al.
Publicado: (2021)

Parkinson’s Disease: Carbidopa, Nausea, and Dyskinesia [Expression of Concern]
por: Hinz M, et al.
Publicado: (2020)

Levodopa en la enfermedad de Parkinson: ¿Qué hemos aprendido?
por: Juri C,Carlos, et al.
Publicado: (2006)

SYNTHESIS AND EVALUATION OF HEPATOPROTECTIVE ACTIVITY OF SOME NEW MANNICH BASES BEARING BENZTRIAZOLE MOIETY
por: RAJASEKARAN,AIYALU, et al.
Publicado: (2010)

A thermophilic microorganism from Deception Island, Antarctica with a thermostable glutamate dehydrogenase activity
por: Flores,Patricio A. M., et al.
Publicado: (2018)

Anti-Inflammatory Effects of the Novel Barbiturate Derivative MHY2699 in an MPTP-Induced Mouse Model of Parkinson’s Disease
por: Seulah Lee, et al.
Publicado: (2021)

Long-Term Depression of Striatal DA Release Induced by mGluRs via Sustained Hyperactivity of Local Cholinergic Interneurons
por: Nicola B. Mercuri, et al.
Publicado: (2021)

In vivo Pharmacokinetic and Anticancer Studies of HH-N25, a Selective Inhibitor of Topoisomerase I, and Hormonal Signaling for Treating Breast Cancer
por: Lawal B, et al.
Publicado: (2021)

Types I and III Parotid Collagen Variations and Serum Biochemical Parameters in Obese Rats Exposed to Monosodium Glutamate
por: Roa,Ignacio, et al.
Publicado: (2020)

Melatonin Attenuates Neuroinflammation by Down-Regulating NLRP3 Inflammasome via a SIRT1-Dependent Pathway in MPTP-Induced Models of Parkinson’s Disease
por: Zheng R, et al.
Publicado: (2021)

Dopamine, a co-regulatory component, bridges the central nervous system and the immune system
por: Mingan Li, et al.
Publicado: (2022)

Parkinson's disease: carbidopa, nausea, and dyskinesia
por: Hinz M, et al.
Publicado: (2014)

The Parkinson’s Disease Death Rate: Carbidopa and Vitamin B6 [Retraction]
por: Hinz M, et al.
Publicado: (2021)

NRF2 Activation and Downstream Effects: Focus on Parkinson’s Disease and Brain Angiotensin
por: Juan A. Parga, et al.
Publicado: (2021)

Pharmacokinetics and safety of posaconazole delayed-release tablets for invasive fungal infections
por: Wiederhold NP
Publicado: (2015)

The Parkinson’s Disease Death Rate: Carbidopa and Vitamin B6 [Expression of Concern]
por: Hinz M, et al.
Publicado: (2020)

Composition of intestinal flora affects the risk relationship between Alzheimer's disease/Parkinson's disease and cancer
por: Zhongci Hang, et al.
Publicado: (2022)

Microglial Activation Mediates Noradrenergic Locus Coeruleus Neurodegeneration via Complement Receptor 3 in a Rotenone-Induced Parkinson’s Disease Mouse Model
por: Jing L, et al.
Publicado: (2021)

The Parkinson's disease death rate: carbidopa and vitamin B6
por: Hinz M, et al.
Publicado: (2014)

Pharmacological Modulation of Nrf2/HO-1 Signaling Pathway as a Therapeutic Target of Parkinson’s Disease
por: Yumin Wang, et al.
Publicado: (2021)

Protective Role of Sarpogrelate in Combination with Bromocriptine and Cabergoline for Treatment of Diabetes in Alloxan-induced Diabetic Rats
por: Mohammed Fouad Shalaby, MD, et al.
Publicado: (2021)

Long-term changes in short-interval intracortical facilitation modulate motor cortex plasticity and L-dopa-induced dyskinesia in Parkinson's disease
por: Andrea Guerra, et al.
Publicado: (2022)

LCC-09, a Novel Salicylanilide Derivative, Exerts Anti-Inflammatory Effect in Vascular Endothelial Cells
por: Angom RS, et al.
Publicado: (2021)

Activation and Inhibition of the NLRP3 Inflammasome by RNA Viruses
por: Choudhury SM, et al.
Publicado: (2021)

LRRK2 inhibitors and their potential in the treatment of Parkinson’s disease: current perspectives
por: Atashrazm F, et al.
Publicado: (2016)