Inhibition of highly pathogenic avian influenza (HPAI) virus by a peptide derived from vFLIP through its direct destabilization of viruses

Abstract The antiviral activities of synthesized Kα2-helix peptide, which was derived from the viral FLICE-like inhibitor protein (vFLIP) of Kaposi’s sarcoma-associated herpesvirus (KSHV), against influenza A virus (IAV) were investigated in vitro and in vivo, and mechanisms of action were suggested...

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Autores principales: Ho-Jin Moon, Chamilani Nikapitiya, Hyun-Cheol Lee, Min-Eun Park, Jae-Hoon Kim, Tae-Hwan Kim, Ji-Eun Yoon, Won-Kyung Cho, Jin Yeul Ma, Chul-Joong Kim, Jae U. Jung, Jong-Soo Lee
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/8c077a47490c45f891fa9dc38f80b75e
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