Genetic architecture and lifetime dynamics of inbreeding depression in a wild mammal

Without understanding the genetic architecture of inbreeding depression, its effects are hard to pinpoint. Long-term data from wild Soay sheep shows that inbreeding manifests in long runs of homozygosity, which made up nearly half of the genome in the most inbred individuals with severe fitness cons...

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Auteurs principaux:	M. A. Stoffel, S. E. Johnston, J. G. Pilkington, J. M. Pemberton
Format:	article
Langue:	EN
Publié:	Nature Portfolio 2021
Sujets:	Science Q
Accès en ligne:	https://doaj.org/article/8c27a50261724d00ae93f0b527c6d79c
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id	oai:doaj.org-article:8c27a50261724d00ae93f0b527c6d79c
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spelling	oai:doaj.org-article:8c27a50261724d00ae93f0b527c6d79c2021-12-02T15:53:08ZGenetic architecture and lifetime dynamics of inbreeding depression in a wild mammal10.1038/s41467-021-23222-92041-1723https://doaj.org/article/8c27a50261724d00ae93f0b527c6d79c2021-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-23222-9https://doaj.org/toc/2041-1723Without understanding the genetic architecture of inbreeding depression, its effects are hard to pinpoint. Long-term data from wild Soay sheep shows that inbreeding manifests in long runs of homozygosity, which made up nearly half of the genome in the most inbred individuals with severe fitness consequences.M. A. StoffelS. E. JohnstonJ. G. PilkingtonJ. M. PembertonNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q M. A. Stoffel S. E. Johnston J. G. Pilkington J. M. Pemberton Genetic architecture and lifetime dynamics of inbreeding depression in a wild mammal
description	Without understanding the genetic architecture of inbreeding depression, its effects are hard to pinpoint. Long-term data from wild Soay sheep shows that inbreeding manifests in long runs of homozygosity, which made up nearly half of the genome in the most inbred individuals with severe fitness consequences.
format	article
author	M. A. Stoffel S. E. Johnston J. G. Pilkington J. M. Pemberton
author_facet	M. A. Stoffel S. E. Johnston J. G. Pilkington J. M. Pemberton
author_sort	M. A. Stoffel
title	Genetic architecture and lifetime dynamics of inbreeding depression in a wild mammal
title_short	Genetic architecture and lifetime dynamics of inbreeding depression in a wild mammal
title_full	Genetic architecture and lifetime dynamics of inbreeding depression in a wild mammal
title_fullStr	Genetic architecture and lifetime dynamics of inbreeding depression in a wild mammal
title_full_unstemmed	Genetic architecture and lifetime dynamics of inbreeding depression in a wild mammal
title_sort	genetic architecture and lifetime dynamics of inbreeding depression in a wild mammal
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/8c27a50261724d00ae93f0b527c6d79c
work_keys_str_mv	AT mastoffel geneticarchitectureandlifetimedynamicsofinbreedingdepressioninawildmammal AT sejohnston geneticarchitectureandlifetimedynamicsofinbreedingdepressioninawildmammal AT jgpilkington geneticarchitectureandlifetimedynamicsofinbreedingdepressioninawildmammal AT jmpemberton geneticarchitectureandlifetimedynamicsofinbreedingdepressioninawildmammal
_version_	1718385520433692672

Genetic architecture and lifetime dynamics of inbreeding depression in a wild mammal

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