Lipid metabolism adaptations are reduced in human compared to murine Schwann cells following injury

The regeneration dynamics following peripheral nerve injury differs among species. Here, the authors compared transcriptomic and lipid metabolism changes in murine and human Schwann cells in vivo and ex vivo sural nerves, underlying their switch from myelinating to repair state following injury.

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Autores principales: Sofia Meyer zu Reckendorf, Christine Brand, Maria T. Pedro, Jutta Hegler, Corinna S. Schilling, Raissa Lerner, Laura Bindila, Gregor Antoniadis, Bernd Knöll
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Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/8c2c6448c4ef49c4819a929191ec28cb
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spelling oai:doaj.org-article:8c2c6448c4ef49c4819a929191ec28cb2021-12-02T14:40:42ZLipid metabolism adaptations are reduced in human compared to murine Schwann cells following injury10.1038/s41467-020-15915-42041-1723https://doaj.org/article/8c2c6448c4ef49c4819a929191ec28cb2020-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-15915-4https://doaj.org/toc/2041-1723The regeneration dynamics following peripheral nerve injury differs among species. Here, the authors compared transcriptomic and lipid metabolism changes in murine and human Schwann cells in vivo and ex vivo sural nerves, underlying their switch from myelinating to repair state following injury.Sofia Meyer zu ReckendorfChristine BrandMaria T. PedroJutta HeglerCorinna S. SchillingRaissa LernerLaura BindilaGregor AntoniadisBernd KnöllNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Sofia Meyer zu Reckendorf
Christine Brand
Maria T. Pedro
Jutta Hegler
Corinna S. Schilling
Raissa Lerner
Laura Bindila
Gregor Antoniadis
Bernd Knöll
Lipid metabolism adaptations are reduced in human compared to murine Schwann cells following injury
description The regeneration dynamics following peripheral nerve injury differs among species. Here, the authors compared transcriptomic and lipid metabolism changes in murine and human Schwann cells in vivo and ex vivo sural nerves, underlying their switch from myelinating to repair state following injury.
format article
author Sofia Meyer zu Reckendorf
Christine Brand
Maria T. Pedro
Jutta Hegler
Corinna S. Schilling
Raissa Lerner
Laura Bindila
Gregor Antoniadis
Bernd Knöll
author_facet Sofia Meyer zu Reckendorf
Christine Brand
Maria T. Pedro
Jutta Hegler
Corinna S. Schilling
Raissa Lerner
Laura Bindila
Gregor Antoniadis
Bernd Knöll
author_sort Sofia Meyer zu Reckendorf
title Lipid metabolism adaptations are reduced in human compared to murine Schwann cells following injury
title_short Lipid metabolism adaptations are reduced in human compared to murine Schwann cells following injury
title_full Lipid metabolism adaptations are reduced in human compared to murine Schwann cells following injury
title_fullStr Lipid metabolism adaptations are reduced in human compared to murine Schwann cells following injury
title_full_unstemmed Lipid metabolism adaptations are reduced in human compared to murine Schwann cells following injury
title_sort lipid metabolism adaptations are reduced in human compared to murine schwann cells following injury
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/8c2c6448c4ef49c4819a929191ec28cb
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