Lipid metabolism adaptations are reduced in human compared to murine Schwann cells following injury
The regeneration dynamics following peripheral nerve injury differs among species. Here, the authors compared transcriptomic and lipid metabolism changes in murine and human Schwann cells in vivo and ex vivo sural nerves, underlying their switch from myelinating to repair state following injury.
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Nature Portfolio
2020
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oai:doaj.org-article:8c2c6448c4ef49c4819a929191ec28cb2021-12-02T14:40:42ZLipid metabolism adaptations are reduced in human compared to murine Schwann cells following injury10.1038/s41467-020-15915-42041-1723https://doaj.org/article/8c2c6448c4ef49c4819a929191ec28cb2020-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-15915-4https://doaj.org/toc/2041-1723The regeneration dynamics following peripheral nerve injury differs among species. Here, the authors compared transcriptomic and lipid metabolism changes in murine and human Schwann cells in vivo and ex vivo sural nerves, underlying their switch from myelinating to repair state following injury.Sofia Meyer zu ReckendorfChristine BrandMaria T. PedroJutta HeglerCorinna S. SchillingRaissa LernerLaura BindilaGregor AntoniadisBernd KnöllNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-15 (2020) |
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Science Q Sofia Meyer zu Reckendorf Christine Brand Maria T. Pedro Jutta Hegler Corinna S. Schilling Raissa Lerner Laura Bindila Gregor Antoniadis Bernd Knöll Lipid metabolism adaptations are reduced in human compared to murine Schwann cells following injury |
description |
The regeneration dynamics following peripheral nerve injury differs among species. Here, the authors compared transcriptomic and lipid metabolism changes in murine and human Schwann cells in vivo and ex vivo sural nerves, underlying their switch from myelinating to repair state following injury. |
format |
article |
author |
Sofia Meyer zu Reckendorf Christine Brand Maria T. Pedro Jutta Hegler Corinna S. Schilling Raissa Lerner Laura Bindila Gregor Antoniadis Bernd Knöll |
author_facet |
Sofia Meyer zu Reckendorf Christine Brand Maria T. Pedro Jutta Hegler Corinna S. Schilling Raissa Lerner Laura Bindila Gregor Antoniadis Bernd Knöll |
author_sort |
Sofia Meyer zu Reckendorf |
title |
Lipid metabolism adaptations are reduced in human compared to murine Schwann cells following injury |
title_short |
Lipid metabolism adaptations are reduced in human compared to murine Schwann cells following injury |
title_full |
Lipid metabolism adaptations are reduced in human compared to murine Schwann cells following injury |
title_fullStr |
Lipid metabolism adaptations are reduced in human compared to murine Schwann cells following injury |
title_full_unstemmed |
Lipid metabolism adaptations are reduced in human compared to murine Schwann cells following injury |
title_sort |
lipid metabolism adaptations are reduced in human compared to murine schwann cells following injury |
publisher |
Nature Portfolio |
publishDate |
2020 |
url |
https://doaj.org/article/8c2c6448c4ef49c4819a929191ec28cb |
work_keys_str_mv |
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