Assessment of Effective Factors In Recurrent Implantation Failure (RIF) Following Assisted Reproductive Technology (ART)

BACKGROUND AND OBJECTIVE: Despite many advances have been made in the assisted reproduction techniques (ART), implantation rate after embryo transfer has not increased significantly. Therefore, this study aims to determine the factors involved in recurrent implantation failure (RIF) following ART. M...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Z Basirat, M Kashifard, Z Aghaei, T Mahouti, S Gh Jorsaraei, M Golsorakhtabar amiri
Formato: article
Lenguaje:EN
FA
Publicado: Babol University of Medical Sciences 2019
Materias:
R
Acceso en línea:https://doaj.org/article/8c32d3d7dc6e4360b99c757c42f6265d
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:8c32d3d7dc6e4360b99c757c42f6265d
record_format dspace
spelling oai:doaj.org-article:8c32d3d7dc6e4360b99c757c42f6265d2021-11-10T08:30:37ZAssessment of Effective Factors In Recurrent Implantation Failure (RIF) Following Assisted Reproductive Technology (ART)1561-41072251-7170https://doaj.org/article/8c32d3d7dc6e4360b99c757c42f6265d2019-12-01T00:00:00Zhttp://jbums.org/article-1-8382-en.htmlhttps://doaj.org/toc/1561-4107https://doaj.org/toc/2251-7170BACKGROUND AND OBJECTIVE: Despite many advances have been made in the assisted reproduction techniques (ART), implantation rate after embryo transfer has not increased significantly. Therefore, this study aims to determine the factors involved in recurrent implantation failure (RIF) following ART. METHODS: In this retrospective study, 80 infertile patients with a history of at least 3 recurrent implantation failure (RIF) following assisted reproductive technology (ART) were referred to Fatemezahra Infertility Center in Babol from March 2006 to March 2013 were selected. The control group also included 80 women who became pregnant following the first IVF. Associated factors of infertility, endocrine disorder and endometriosis were recorded and their effect on RIF was assessed in both groups. FINDINGS: The mean BMI was 26.39±3.63 in the case group and 26.77±4.49 in the control group. Body mass index (BMI) >30 increased the risk of RIF significantly (p=0.001). After adjusting for the effects of other possible confounding factors, the odds ratio of obesity on RIF was 1.09(0.91-1.19) 95% CI which was not significant (p=0.06). There were no significant differences among type and cause of infertility, endocrine abnormalities, uterine malformations, endometriosis and polycystic ovary with RIF. CONCLUSION: According to our findings, BMI, type and cause of infertility, endocrine disorders, uterine abnormalities, endometriosis, and polycystic ovary were not effective on recurrent implantation failure.Z BasiratM KashifardZ AghaeiT MahoutiS Gh JorsaraeiM Golsorakhtabar amiriBabol University of Medical Sciencesarticleembryo implantationobesitybody mass indexinfertility.MedicineRMedicine (General)R5-920ENFAMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, Vol 21, Iss 1, Pp 383-389 (2019)
institution DOAJ
collection DOAJ
language EN
FA
topic embryo implantation
obesity
body mass index
infertility.
Medicine
R
Medicine (General)
R5-920
spellingShingle embryo implantation
obesity
body mass index
infertility.
Medicine
R
Medicine (General)
R5-920
Z Basirat
M Kashifard
Z Aghaei
T Mahouti
S Gh Jorsaraei
M Golsorakhtabar amiri
Assessment of Effective Factors In Recurrent Implantation Failure (RIF) Following Assisted Reproductive Technology (ART)
description BACKGROUND AND OBJECTIVE: Despite many advances have been made in the assisted reproduction techniques (ART), implantation rate after embryo transfer has not increased significantly. Therefore, this study aims to determine the factors involved in recurrent implantation failure (RIF) following ART. METHODS: In this retrospective study, 80 infertile patients with a history of at least 3 recurrent implantation failure (RIF) following assisted reproductive technology (ART) were referred to Fatemezahra Infertility Center in Babol from March 2006 to March 2013 were selected. The control group also included 80 women who became pregnant following the first IVF. Associated factors of infertility, endocrine disorder and endometriosis were recorded and their effect on RIF was assessed in both groups. FINDINGS: The mean BMI was 26.39±3.63 in the case group and 26.77±4.49 in the control group. Body mass index (BMI) >30 increased the risk of RIF significantly (p=0.001). After adjusting for the effects of other possible confounding factors, the odds ratio of obesity on RIF was 1.09(0.91-1.19) 95% CI which was not significant (p=0.06). There were no significant differences among type and cause of infertility, endocrine abnormalities, uterine malformations, endometriosis and polycystic ovary with RIF. CONCLUSION: According to our findings, BMI, type and cause of infertility, endocrine disorders, uterine abnormalities, endometriosis, and polycystic ovary were not effective on recurrent implantation failure.
format article
author Z Basirat
M Kashifard
Z Aghaei
T Mahouti
S Gh Jorsaraei
M Golsorakhtabar amiri
author_facet Z Basirat
M Kashifard
Z Aghaei
T Mahouti
S Gh Jorsaraei
M Golsorakhtabar amiri
author_sort Z Basirat
title Assessment of Effective Factors In Recurrent Implantation Failure (RIF) Following Assisted Reproductive Technology (ART)
title_short Assessment of Effective Factors In Recurrent Implantation Failure (RIF) Following Assisted Reproductive Technology (ART)
title_full Assessment of Effective Factors In Recurrent Implantation Failure (RIF) Following Assisted Reproductive Technology (ART)
title_fullStr Assessment of Effective Factors In Recurrent Implantation Failure (RIF) Following Assisted Reproductive Technology (ART)
title_full_unstemmed Assessment of Effective Factors In Recurrent Implantation Failure (RIF) Following Assisted Reproductive Technology (ART)
title_sort assessment of effective factors in recurrent implantation failure (rif) following assisted reproductive technology (art)
publisher Babol University of Medical Sciences
publishDate 2019
url https://doaj.org/article/8c32d3d7dc6e4360b99c757c42f6265d
work_keys_str_mv AT zbasirat assessmentofeffectivefactorsinrecurrentimplantationfailureriffollowingassistedreproductivetechnologyart
AT mkashifard assessmentofeffectivefactorsinrecurrentimplantationfailureriffollowingassistedreproductivetechnologyart
AT zaghaei assessmentofeffectivefactorsinrecurrentimplantationfailureriffollowingassistedreproductivetechnologyart
AT tmahouti assessmentofeffectivefactorsinrecurrentimplantationfailureriffollowingassistedreproductivetechnologyart
AT sghjorsaraei assessmentofeffectivefactorsinrecurrentimplantationfailureriffollowingassistedreproductivetechnologyart
AT mgolsorakhtabaramiri assessmentofeffectivefactorsinrecurrentimplantationfailureriffollowingassistedreproductivetechnologyart
_version_ 1718440396805111808