Protective Effect of Uric Acid on ox-LDL-Induced HUVECs Injury via Keap1-Nrf2-ARE Pathway

Uric acid is an effective antioxidant. Oxidized low-density lipoprotein (ox-LDL) is derived from circulating LDL and promotes atherosclerosis. The Keap1-Nrf2-ARE pathway is a key body pathway involved in protection against internal and external oxidative damages. The role of uric acid on vascular en...

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Bibliographic Details
Main Authors: Yajuan Lin, Yunpeng Xie, Zhujing Hao, Hailian Bi, Yang Liu, Xiaolei Yang, Yunlong Xia
Format: article
Language:EN
Published: Hindawi Limited 2021
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Online Access:https://doaj.org/article/8c37beae5ce74cb686f0c90bff3a6a10
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