Lack of XPC leads to a shift between respiratory complexes I and II but sensitizes cells to mitochondrial stress
Abstract Genomic instability drives tumorigenesis and DNA repair defects are associated with elevated cancer. Metabolic alterations are also observed during tumorigenesis, although a causal relationship between these has not been clearly established. Xeroderma pigmentosum (XP) is a DNA repair diseas...
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Autores principales: | Mateus P. Mori, Rute A. P. Costa, Daniela T. Soltys, Thiago de S. Freire, Franco A. Rossato, Ignácio Amigo, Alicia J. Kowaltowski, Aníbal E. Vercesi, Nadja C. de Souza-Pinto |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
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Materias: | |
Acceso en línea: | https://doaj.org/article/8c3abd91e76c4e26a1355a84576051ac |
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