Norovirus Escape from Broadly Neutralizing Antibodies Is Limited to Allostery-Like Mechanisms
ABSTRACT Ideal antiviral vaccines elicit antibodies (Abs) with broad strain recognition that bind to regions that are difficult to mutate for escape. Using 10 murine norovirus (MNV) strains and 5 human norovirus (HuNoV) virus-like particles (VLPs), we identified monoclonal antibody (MAb) 2D3, which...
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| Main Authors: | , , , , , , , , |
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| Format: | article |
| Language: | EN |
| Published: |
American Society for Microbiology
2017
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| Subjects: | |
| Online Access: | https://doaj.org/article/8c3e915739ee40cdb50d1aac4ea2b75c |
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