Gold nanoclusters-assisted delivery of NGF siRNA for effective treatment of pancreatic cancer

Gold nanoclusters-assisted delivery of NGF siRNA for effective treatment of pancreatic cancer

Nerve growth factor (NGF) contributes to the sustained growth and metastasis of pancreatic cancer cells. Here, the authors develop a gold nanocluster-coupled siRNA against NGF that efficiently silences theNGFgene and inhibits tumour growth of pancreatic cancer in mice.

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Detalles Bibliográficos
Autores principales: Yifeng Lei, Lixue Tang, Yangzhouyun Xie, Yunlei Xianyu, Lingmin Zhang, Peng Wang, Yoh Hamada, Kai Jiang, Wenfu Zheng, Xingyu Jiang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Science
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Acceso en línea:https://doaj.org/article/8c4855616b44477eaaf1566e42217856
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