Molecular characteristics and tumorigenicity of ascites‐derived tumor cells: mitochondrial oxidative phosphorylation as a novel therapy target in ovarian cancer

Ovarian cancer disseminates primarily intraperitoneally. Detached tumor cell aggregates (spheroids) from the primary tumor are regarded as ‘metastatic units’ that exhibit a low sensitivity to classical chemotherapy, probably due to their unique molecular characteristics. We have analyzed the cellula...

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Autores principales: Yi Ding, Vera Labitzky, Karen Legler, Minyue Qi, Udo Schumacher, Barbara Schmalfeldt, Christine Stürken, Leticia Oliveira‐Ferrer
Formato: article
Lenguaje:EN
Publicado: Wiley 2021
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Acceso en línea:https://doaj.org/article/8c4a537d10654c95a91174b3a640d61f
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