Ecological niche adaptation of Salmonella Typhimurium U288 is associated with altered pathogenicity and reduced zoonotic potential

Mark Kirkwood et al. take an epidemiological, genomic, phylogenetic, and experimental approach to assess the evolutionary origins and virulence of the U288 and ST34 isolates of Salmonella enterica in affecting livestock and potentially humans. Their results indicate that the molecular evolution of t...

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Autores principales:	Mark Kirkwood, Prerna Vohra, Matt Bawn, Gaëtan Thilliez, Hannah Pye, Jennifer Tanner, Cosmin Chintoan-Uta, Priscilla Branchu, Liljana Petrovska, Timothy Dallman, Neil Hall, Mark P. Stevens, Robert A. Kingsley
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/8c52b28de3c14eabb4f9ecfc56e2eac4
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spelling	oai:doaj.org-article:8c52b28de3c14eabb4f9ecfc56e2eac42021-12-02T18:28:59ZEcological niche adaptation of Salmonella Typhimurium U288 is associated with altered pathogenicity and reduced zoonotic potential10.1038/s42003-021-02013-42399-3642https://doaj.org/article/8c52b28de3c14eabb4f9ecfc56e2eac42021-04-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02013-4https://doaj.org/toc/2399-3642Mark Kirkwood et al. take an epidemiological, genomic, phylogenetic, and experimental approach to assess the evolutionary origins and virulence of the U288 and ST34 isolates of Salmonella enterica in affecting livestock and potentially humans. Their results indicate that the molecular evolution of these isolates is associated with altered pathogenicity in pigs and reduced zoonotic potential of U288.Mark KirkwoodPrerna VohraMatt BawnGaëtan ThilliezHannah PyeJennifer TannerCosmin Chintoan-UtaPriscilla BranchuLiljana PetrovskaTimothy DallmanNeil HallMark P. StevensRobert A. KingsleyNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-15 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 Mark Kirkwood Prerna Vohra Matt Bawn Gaëtan Thilliez Hannah Pye Jennifer Tanner Cosmin Chintoan-Uta Priscilla Branchu Liljana Petrovska Timothy Dallman Neil Hall Mark P. Stevens Robert A. Kingsley Ecological niche adaptation of Salmonella Typhimurium U288 is associated with altered pathogenicity and reduced zoonotic potential
description	Mark Kirkwood et al. take an epidemiological, genomic, phylogenetic, and experimental approach to assess the evolutionary origins and virulence of the U288 and ST34 isolates of Salmonella enterica in affecting livestock and potentially humans. Their results indicate that the molecular evolution of these isolates is associated with altered pathogenicity in pigs and reduced zoonotic potential of U288.
format	article
author	Mark Kirkwood Prerna Vohra Matt Bawn Gaëtan Thilliez Hannah Pye Jennifer Tanner Cosmin Chintoan-Uta Priscilla Branchu Liljana Petrovska Timothy Dallman Neil Hall Mark P. Stevens Robert A. Kingsley
author_facet	Mark Kirkwood Prerna Vohra Matt Bawn Gaëtan Thilliez Hannah Pye Jennifer Tanner Cosmin Chintoan-Uta Priscilla Branchu Liljana Petrovska Timothy Dallman Neil Hall Mark P. Stevens Robert A. Kingsley
author_sort	Mark Kirkwood
title	Ecological niche adaptation of Salmonella Typhimurium U288 is associated with altered pathogenicity and reduced zoonotic potential
title_short	Ecological niche adaptation of Salmonella Typhimurium U288 is associated with altered pathogenicity and reduced zoonotic potential
title_full	Ecological niche adaptation of Salmonella Typhimurium U288 is associated with altered pathogenicity and reduced zoonotic potential
title_fullStr	Ecological niche adaptation of Salmonella Typhimurium U288 is associated with altered pathogenicity and reduced zoonotic potential
title_full_unstemmed	Ecological niche adaptation of Salmonella Typhimurium U288 is associated with altered pathogenicity and reduced zoonotic potential
title_sort	ecological niche adaptation of salmonella typhimurium u288 is associated with altered pathogenicity and reduced zoonotic potential
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/8c52b28de3c14eabb4f9ecfc56e2eac4
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Ecological niche adaptation of Salmonella Typhimurium U288 is associated with altered pathogenicity and reduced zoonotic potential

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