Fluorescent Chitosan Modified with Heterocyclic Aromatic Dyes
Chitosan is a valuable, functional, and biodegradable polysaccharide that can be modified to expand its applications. This work aimed to obtain chitosan derivatives with fluorescent properties. Three heterocyclic aromatic dyes (based on benzimidazole, benzoxazole, and benzothiazole) were synthesized...
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MDPI AG
2021
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oai:doaj.org-article:8c5496b0b96b4d088cc771f9da83f2932021-11-11T18:00:14ZFluorescent Chitosan Modified with Heterocyclic Aromatic Dyes10.3390/ma142164291996-1944https://doaj.org/article/8c5496b0b96b4d088cc771f9da83f2932021-10-01T00:00:00Zhttps://www.mdpi.com/1996-1944/14/21/6429https://doaj.org/toc/1996-1944Chitosan is a valuable, functional, and biodegradable polysaccharide that can be modified to expand its applications. This work aimed to obtain chitosan derivatives with fluorescent properties. Three heterocyclic aromatic dyes (based on benzimidazole, benzoxazole, and benzothiazole) were synthesized and used for the chemical modification of chitosan. Emission spectroscopy revealed the strong fluorescent properties of the obtained chitosan derivatives even at a low <i>N</i>-substitution degree of the dye. The effect of high-energy ultraviolet radiation (UV–C) on modified chitosan samples was studied in solution with UV–Vis spectroscopy and in the solid state with FTIR spectroscopy. Moreover, cytotoxicity towards three different cell types was evaluated to estimate the possibilities of biomedical applications of such fluorescent chitosan-based materials. It was found that the three new derivatives of chitosan were characterized by good resistance to UV–C, which suggests the possibility of using these materials in medicine and various industrial sectors.Halina KaczmarekAgnieszka Tafelska-KaczmarekKatarzyna RoszekJoanna CzarneckaBeata JędrzejewskaKatarzyna ZblewskaMDPI AGarticlechitosan modificationfluorescenceheterocyclic aromatic compoundsUV–C irradiationcytotoxicityTechnologyTElectrical engineering. Electronics. Nuclear engineeringTK1-9971Engineering (General). Civil engineering (General)TA1-2040MicroscopyQH201-278.5Descriptive and experimental mechanicsQC120-168.85ENMaterials, Vol 14, Iss 6429, p 6429 (2021) |
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DOAJ |
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DOAJ |
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EN |
| topic |
chitosan modification fluorescence heterocyclic aromatic compounds UV–C irradiation cytotoxicity Technology T Electrical engineering. Electronics. Nuclear engineering TK1-9971 Engineering (General). Civil engineering (General) TA1-2040 Microscopy QH201-278.5 Descriptive and experimental mechanics QC120-168.85 |
| spellingShingle |
chitosan modification fluorescence heterocyclic aromatic compounds UV–C irradiation cytotoxicity Technology T Electrical engineering. Electronics. Nuclear engineering TK1-9971 Engineering (General). Civil engineering (General) TA1-2040 Microscopy QH201-278.5 Descriptive and experimental mechanics QC120-168.85 Halina Kaczmarek Agnieszka Tafelska-Kaczmarek Katarzyna Roszek Joanna Czarnecka Beata Jędrzejewska Katarzyna Zblewska Fluorescent Chitosan Modified with Heterocyclic Aromatic Dyes |
| description |
Chitosan is a valuable, functional, and biodegradable polysaccharide that can be modified to expand its applications. This work aimed to obtain chitosan derivatives with fluorescent properties. Three heterocyclic aromatic dyes (based on benzimidazole, benzoxazole, and benzothiazole) were synthesized and used for the chemical modification of chitosan. Emission spectroscopy revealed the strong fluorescent properties of the obtained chitosan derivatives even at a low <i>N</i>-substitution degree of the dye. The effect of high-energy ultraviolet radiation (UV–C) on modified chitosan samples was studied in solution with UV–Vis spectroscopy and in the solid state with FTIR spectroscopy. Moreover, cytotoxicity towards three different cell types was evaluated to estimate the possibilities of biomedical applications of such fluorescent chitosan-based materials. It was found that the three new derivatives of chitosan were characterized by good resistance to UV–C, which suggests the possibility of using these materials in medicine and various industrial sectors. |
| format |
article |
| author |
Halina Kaczmarek Agnieszka Tafelska-Kaczmarek Katarzyna Roszek Joanna Czarnecka Beata Jędrzejewska Katarzyna Zblewska |
| author_facet |
Halina Kaczmarek Agnieszka Tafelska-Kaczmarek Katarzyna Roszek Joanna Czarnecka Beata Jędrzejewska Katarzyna Zblewska |
| author_sort |
Halina Kaczmarek |
| title |
Fluorescent Chitosan Modified with Heterocyclic Aromatic Dyes |
| title_short |
Fluorescent Chitosan Modified with Heterocyclic Aromatic Dyes |
| title_full |
Fluorescent Chitosan Modified with Heterocyclic Aromatic Dyes |
| title_fullStr |
Fluorescent Chitosan Modified with Heterocyclic Aromatic Dyes |
| title_full_unstemmed |
Fluorescent Chitosan Modified with Heterocyclic Aromatic Dyes |
| title_sort |
fluorescent chitosan modified with heterocyclic aromatic dyes |
| publisher |
MDPI AG |
| publishDate |
2021 |
| url |
https://doaj.org/article/8c5496b0b96b4d088cc771f9da83f293 |
| work_keys_str_mv |
AT halinakaczmarek fluorescentchitosanmodifiedwithheterocyclicaromaticdyes AT agnieszkatafelskakaczmarek fluorescentchitosanmodifiedwithheterocyclicaromaticdyes AT katarzynaroszek fluorescentchitosanmodifiedwithheterocyclicaromaticdyes AT joannaczarnecka fluorescentchitosanmodifiedwithheterocyclicaromaticdyes AT beatajedrzejewska fluorescentchitosanmodifiedwithheterocyclicaromaticdyes AT katarzynazblewska fluorescentchitosanmodifiedwithheterocyclicaromaticdyes |
| _version_ |
1718431956372291584 |