Acute administration of catalase targeted to ICAM-1 attenuates neuropathology in experimental traumatic brain injury

Acute administration of catalase targeted to ICAM-1 attenuates neuropathology in experimental traumatic brain injury

Abstract Traumatic brain injury (TBI) contributes to one third of injury related deaths in the US. Treatment strategies for TBI are supportive, and the pathophysiology is not fully understood. Secondary mechanisms of injury in TBI, such as oxidative stress and inflammation, are points at which inter...

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Autores principales: Evan M. Lutton, Roshanak Razmpour, Allison M. Andrews, Lee Anne Cannella, Young-Jin Son, Vladimir V. Shuvaev, Vladimir R. Muzykantov, Servio H. Ramirez
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Medicine
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Science
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Acceso en línea:https://doaj.org/article/8c574c0d411e41d5b652a7758170ba4f
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