A glucagon analogue decreases body weight in mice via signalling in the liver

Abstract Glucagon receptor agonists show promise as components of next generation metabolic syndrome pharmacotherapies. However, the biology of glucagon action is complex, controversial, and likely context dependent. As such, a better understanding of chronic glucagon receptor (GCGR) agonism is esse...

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Autores principales: Charlotte E. Hinds, Bryn M. Owen, David C. D. Hope, Philip Pickford, Ben Jones, Tricia M. Tan, James S. Minnion, Stephen R. Bloom
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/8c5c2844790d4fd68305731ce059ecb1
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