Contribution of Cytidine Deaminase to Thymidylate Biosynthesis in <named-content content-type="genus-species">Trypanosoma brucei</named-content>: Intracellular Localization and Properties of the Enzyme

ABSTRACT Cytidine deaminase (CDA) is a pyrimidine salvage enzyme that catalyzes cytidine and deoxycytidine hydrolytic deamination to yield uridine and deoxyuridine. Here we report the biochemical characterization of Trypanosoma brucei CDA as an enzyme within the tetrameric class of the CDA family th...

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Main Authors: Ana Moro-Bulnes, Víctor M. Castillo-Acosta, Maria Valente, Juana Carrero-Lérida, Guiomar Pérez-Moreno, Luis Miguel Ruiz-Pérez, Dolores González-Pacanowska
Format: article
Language:EN
Published: American Society for Microbiology 2019
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Online Access:https://doaj.org/article/8c654b3d67484ac68b293f3a675cf62d
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