Zinc-binding to the cytoplasmic PAS domain regulates the essential WalK histidine kinase of Staphylococcus aureus

Código QR

Zinc-binding to the cytoplasmic PAS domain regulates the essential WalK histidine kinase of Staphylococcus aureus

WalKR is an essential two-component regulator that controls peptidoglycan synthesis in the human pathogen Staphylococcus aureus. Here, the authors provide biochemical, structural, and functional evidence supporting that the binding of a zinc ion inhibits autophosphorylation and thus alters WalKR reg...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Ian R. Monk, Nausad Shaikh, Stephanie L. Begg, Mike Gajdiss, Liam K. R. Sharkey, Jean Y. H. Lee, Sacha J. Pidot, Torsten Seemann, Michael Kuiper, Brit Winnen, Rikki Hvorup, Brett M. Collins, Gabriele Bierbaum, Saumya R. Udagedara, Jacqueline R. Morey, Neha Pulyani, Benjamin P. Howden, Megan J. Maher, Christopher A. McDevitt, Glenn F. King, Timothy P. Stinear
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/8c79c77e7e1c43c2b593eb5939e70c11
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares

Correspondence: Spontaneous secondary mutations confound analysis of the essential two-component system WalKR in Staphylococcus aureus
por: Ian R. Monk, et al.
Publicado: (2017)

Evolution of multidrug resistance during Staphylococcus aureus infection involves mutation of the essential two component regulator WalKR.
por: Benjamin P Howden, et al.
Publicado: (2011)

Una teoría postcolonial de México, Wal-Mart y la idea de progreso. La invasión de los wal-marcianos
por: Lenneke Schils
Publicado: (2008)

Mining the Methylome Reveals Extensive Diversity in <named-content content-type="genus-species">Staphylococcus epidermidis</named-content> Restriction Modification
por: Jean Y. H. Lee, et al.
Publicado: (2019)

V. V. von Wal as Head of Vilnius Province in 1901—1902
por: M. N. Krot
Publicado: (2021)

Convergent Evolution Driven by Rifampin Exacerbates the Global Burden of Drug-Resistant <named-content content-type="genus-species">Staphylococcus aureus</named-content>
por: Romain Guérillot, et al.
Publicado: (2018)

Complete Bypass of Restriction Systems for Major <named-content content-type="genus-species">Staphylococcus aureus</named-content> Lineages
por: Ian R. Monk, et al.
Publicado: (2015)

Erratum for Monk et al., Complete Bypass of Restriction Systems for Major <named-content content-type="genus-species">Staphylococcus aureus</named-content> Lineages
por: Ian R. Monk, et al.
Publicado: (2016)

Structure and mechanism of the essential two-component signal-transduction system WalKR in Staphylococcus aureus
por: Quanjiang Ji, et al.
Publicado: (2016)

Comparative Transcriptomic and Functional Assessments of Linezolid-Responsive Small RNA Genes in <named-content content-type="genus-species">Staphylococcus aureus</named-content>
por: Wei Gao, et al.
Publicado: (2020)

In Situ Determination of Droplet and Nanoparticle Size Distributions in Spray Flame Synthesis by Wide-Angle Light Scattering (WALS)
por: Simon Aßmann, et al.
Publicado: (2021)

Retraction Note: Structure and mechanism of the essential two-component signal-transduction system WalKR in Staphylococcus aureus
por: Quanjiang Ji, et al.
Publicado: (2017)

In vitro activity of SPR719 against Mycobacterium ulcerans, Mycobacterium marinum and Mycobacterium chimaera.
por: Sacha J Pidot, et al.
Publicado: (2021)

Optogenetics in preclinical neuroscience and psychiatry research: recent insights and potential applications
por: McDevitt RA, et al.
Publicado: (2014)

Comprehensive Genomic Investigation of Adaptive Mutations Driving the Low-Level Oxacillin Resistance Phenotype in <named-content content-type="genus-species">Staphylococcus aureus</named-content>
por: Stefano G. Giulieri, et al.
Publicado: (2020)

Extracellular zinc competitively inhibits manganese uptake and compromises oxidative stress management in Streptococcus pneumoniae.
por: Bart A Eijkelkamp, et al.
Publicado: (2014)

Convergent Adaptation in the Dominant Global Hospital Clone ST239 of Methicillin-Resistant <named-content content-type="genus-species">Staphylococcus aureus</named-content>
por: Sarah L. Baines, et al.
Publicado: (2015)

Author Correction: Dynamic intercellular transport modulates the spatial patterning of differentiation during early neural commitment
por: Chad M. Glen, et al.
Publicado: (2018)

Dynamic intercellular transport modulates the spatial patterning of differentiation during early neural commitment
por: Chad M. Glen, et al.
Publicado: (2018)

How RNA transcripts coordinate DNA recombination and repair
por: Shane McDevitt, et al.
Publicado: (2018)

Genomic Insights to Control the Emergence of Vancomycin-Resistant Enterococci
por: Benjamin P. Howden, et al.
Publicado: (2013)

Ultrasound Assessment of Placenta Accreta Spectrum (PAS), Clinical Management of PAS in Our Society IS-PAS: Minutes of 2020 Online International Workshop on PAS
por: Frederic Chantraine, et al.
Publicado: (2021)

Synthesis, pharmacokinetics, and biological use of lysine-modified single-walled carbon nanotubes [Erratum]
por: Mulvey JJ, et al.
Publicado: (2015)

Synthesis, pharmacokinetics, and biological use of lysine-modified single-walled carbon nanotubes
por: Mulvey JJ, et al.
Publicado: (2014)

Tanfidz Idarah Waqf an-Naqdi (Dirasah Halah fi Wihdatul Mu’awanah wal Jam’u Amwalu Zakah wa Infaq wa Shadaqah wa Waqf Baitul Maal Hidayatullah Madiun ‘Aam 2019-2020)
por: Aqif Khilmia
Publicado: (2020)

Genomewide Profiling of the <named-content content-type="genus-species">Enterococcus faecalis</named-content> Transcriptional Response to Teixobactin Reveals CroRS as an Essential Regulator of Antimicrobial Tolerance
por: Rachel L. Darnell, et al.
Publicado: (2019)

A novel sampling approach to estimating abundance of low‐density and observable species
por: Molly C. McDevitt, et al.
Publicado: (2021)

The effects of amine-modified single-walled carbon nanotubes on the mouse microbiota
por: Mulvey JJ, et al.
Publicado: (2018)

Reconstruction of the Genomes of Drug-Resistant Pathogens for Outbreak Investigation through Metagenomic Sequencing
por: Andre Mu, et al.
Publicado: (2019)

A Trap-Door Mechanism for Zinc Acquisition by <i>Streptococcus pneumoniae</i> AdcA
por: Zhenyao Luo, et al.
Publicado: (2021)

Reseña de "La cultura Wal Mart. La historia de una nueva generación de líderes que convirtió el legado de Sam Walton en la compañía número 1 del mundo" de Robert Slater
por: Carmen Bocanegra Gastélum
Publicado: (2007)

Human hippocampal replay during rest prioritizes weakly learned information and predicts memory performance
por: Anna C. Schapiro, et al.
Publicado: (2018)

Editorial: Experiments and Simulations: A Pas de Deux to Unravel Biological Function
por: Maya Topf, et al.
Publicado: (2021)

Sustaining the integrity of the threatened self: A cluster-randomised trial among social assistance applicants in the Netherlands.
por: Mira Bierbaum, et al.
Publicado: (2021)

Two novel point mutations in clinical Staphylococcus aureus reduce linezolid susceptibility and switch on the stringent response to promote persistent infection.
por: Wei Gao, et al.
Publicado: (2010)

Autoinducer 2 Signaling via the Phosphotransferase FruA Drives Galactose Utilization by <italic toggle="yes">Streptococcus pneumoniae</italic>, Resulting in Hypervirulence
por: Claudia Trappetti, et al.
Publicado: (2017)

PAS Domain Protein Pas3 Interacts with the Chromatin Modifier Bre1 in Regulating Cryptococcal Morphogenesis
por: Youbao Zhao, et al.
Publicado: (2018)

Niche Partitioning between Coastal and Offshore Shelf Waters Results in Differential Expression of Alkane and Polycyclic Aromatic Hydrocarbon Catabolic Pathways
por: Shawn M. Doyle, et al.
Publicado: (2020)

Bioinformatic Mapping of Opine-Like Zincophore Biosynthesis in Bacteria
por: Jacqueline R. Morey, et al.
Publicado: (2020)

Identification of Novel <italic toggle="yes">Acinetobacter baumannii</italic> Host Fatty Acid Stress Adaptation Strategies
por: Jhih-Hang Jiang, et al.
Publicado: (2019)