Heparan sulfates facilitate harmless amyloidogenic fibril formation interacting with elastin-like peptides

Abstract Heparan sulfates (HSs) modulate tissue elasticity in physiopathological conditions by interacting with various matrix constituents as tropoelastin and elastin-derived peptides. HSs bind also to protein moieties accelerating amyloid formation and influencing cytotoxic properties of insoluble...

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Auteurs principaux: Federica Boraldi, Pasquale Moscarelli, Brigida Bochicchio, Antonietta Pepe, Anna M. Salvi, Daniela Quaglino
Format: article
Langue:EN
Publié: Nature Portfolio 2018
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R
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Accès en ligne:https://doaj.org/article/8c820a60bdf24a928d8f6ac0b53ba66d
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