How to achieve a higher selection plateau in forest tree breeding? Fostering heterozygote × homozygote relationships in optimal contribution selection in the case study of Populus nigra

Abstract In breeding, optimal contribution selection (OCS) is one of the most effective strategies to balance short‐ and long‐term genetic responses, by maximizing genetic gain and minimizing global coancestry. Considering genetic diversity in the selection dynamic—through coancestry—is undoubtedly...

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Autores principales:	Mathieu Tiret, Marie Pégard, Leopoldo Sánchez
Formato:	article
Lenguaje:	EN
Publicado:	Wiley 2021
Materias:	genomic selection heterozygote × homozygote relationship optimal contribution selection quantitative genetics simulation Evolution QH359-425
Acceso en línea:	https://doaj.org/article/8c92519f3a604c2c984b97858784fcca
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spelling	oai:doaj.org-article:8c92519f3a604c2c984b97858784fcca2021-11-15T07:15:49ZHow to achieve a higher selection plateau in forest tree breeding? Fostering heterozygote × homozygote relationships in optimal contribution selection in the case study of Populus nigra1752-457110.1111/eva.13300https://doaj.org/article/8c92519f3a604c2c984b97858784fcca2021-11-01T00:00:00Zhttps://doi.org/10.1111/eva.13300https://doaj.org/toc/1752-4571Abstract In breeding, optimal contribution selection (OCS) is one of the most effective strategies to balance short‐ and long‐term genetic responses, by maximizing genetic gain and minimizing global coancestry. Considering genetic diversity in the selection dynamic—through coancestry—is undoubtedly the reason for the success of OCS, as it avoids preliminary loss of favorable alleles. Originally formulated with the pedigree relationship matrix, global coancestry can nowadays be assessed with one of the possible formulations of the realized genomic relationship matrix. Most formulations were optimized for genomic evaluation, but few for the management of coancestry. We introduce here an alternative formulation specifically developed for genomic OCS (GOCS), intended to better control heterozygous loci, and thus better account for Mendelian sampling. We simulated a multigeneration breeding program with mate allocation and under GOCS for twenty generations, solved with quadratic programming. With the case study of Populus nigra, we have shown that, although the dynamic was mainly determined by the trade‐off between genetic gain and genetic diversity, better formulations of the genomic relationship matrix, especially those fostering individuals carrying multiple heterozygous loci, can lead to better short‐term genetic gain and a higher selection plateau.Mathieu TiretMarie PégardLeopoldo SánchezWileyarticlegenomic selectionheterozygote × homozygote relationshipoptimal contribution selectionquantitative geneticssimulationEvolutionQH359-425ENEvolutionary Applications, Vol 14, Iss 11, Pp 2635-2646 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	genomic selection heterozygote × homozygote relationship optimal contribution selection quantitative genetics simulation Evolution QH359-425
spellingShingle	genomic selection heterozygote × homozygote relationship optimal contribution selection quantitative genetics simulation Evolution QH359-425 Mathieu Tiret Marie Pégard Leopoldo Sánchez How to achieve a higher selection plateau in forest tree breeding? Fostering heterozygote × homozygote relationships in optimal contribution selection in the case study of Populus nigra
description	Abstract In breeding, optimal contribution selection (OCS) is one of the most effective strategies to balance short‐ and long‐term genetic responses, by maximizing genetic gain and minimizing global coancestry. Considering genetic diversity in the selection dynamic—through coancestry—is undoubtedly the reason for the success of OCS, as it avoids preliminary loss of favorable alleles. Originally formulated with the pedigree relationship matrix, global coancestry can nowadays be assessed with one of the possible formulations of the realized genomic relationship matrix. Most formulations were optimized for genomic evaluation, but few for the management of coancestry. We introduce here an alternative formulation specifically developed for genomic OCS (GOCS), intended to better control heterozygous loci, and thus better account for Mendelian sampling. We simulated a multigeneration breeding program with mate allocation and under GOCS for twenty generations, solved with quadratic programming. With the case study of Populus nigra, we have shown that, although the dynamic was mainly determined by the trade‐off between genetic gain and genetic diversity, better formulations of the genomic relationship matrix, especially those fostering individuals carrying multiple heterozygous loci, can lead to better short‐term genetic gain and a higher selection plateau.
format	article
author	Mathieu Tiret Marie Pégard Leopoldo Sánchez
author_facet	Mathieu Tiret Marie Pégard Leopoldo Sánchez
author_sort	Mathieu Tiret
title	How to achieve a higher selection plateau in forest tree breeding? Fostering heterozygote × homozygote relationships in optimal contribution selection in the case study of Populus nigra
title_short	How to achieve a higher selection plateau in forest tree breeding? Fostering heterozygote × homozygote relationships in optimal contribution selection in the case study of Populus nigra
title_full	How to achieve a higher selection plateau in forest tree breeding? Fostering heterozygote × homozygote relationships in optimal contribution selection in the case study of Populus nigra
title_fullStr	How to achieve a higher selection plateau in forest tree breeding? Fostering heterozygote × homozygote relationships in optimal contribution selection in the case study of Populus nigra
title_full_unstemmed	How to achieve a higher selection plateau in forest tree breeding? Fostering heterozygote × homozygote relationships in optimal contribution selection in the case study of Populus nigra
title_sort	how to achieve a higher selection plateau in forest tree breeding? fostering heterozygote × homozygote relationships in optimal contribution selection in the case study of populus nigra
publisher	Wiley
publishDate	2021
url	https://doaj.org/article/8c92519f3a604c2c984b97858784fcca
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How to achieve a higher selection plateau in forest tree breeding? Fostering heterozygote × homozygote relationships in optimal contribution selection in the case study of Populus nigra

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