An overview of mice models: a key for understanding subtypes of mania
Animal models have been broadly used in the study of pathophysiology and molecular and neurochemical pathways in neuropsychiatric diseases. Different approaches have used both consanguineous and non-consanguineous mice models to model behavioral patterns associated with the maniac spectrum. However,...
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Universidad de San Buenaventura
2016
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oai:doaj.org-article:8c9b86a715954fd88ad3fbb66f6e89d22021-11-17T02:21:53ZAn overview of mice models: a key for understanding subtypes of mania2011-20842011-7922https://doaj.org/article/8c9b86a715954fd88ad3fbb66f6e89d22016-07-01T00:00:00Zhttps://revistas.usb.edu.co/index.php/IJPR/article/view/2648https://doaj.org/toc/2011-2084https://doaj.org/toc/2011-7922Animal models have been broadly used in the study of pathophysiology and molecular and neurochemical pathways in neuropsychiatric diseases. Different approaches have used both consanguineous and non-consanguineous mice models to model behavioral patterns associated with the maniac spectrum. However, the disadvantages of validating clinical and experimental protocols have hindered the replication of these studies. In this article, the advantages and disadvantages of using consanguineous lines and non-consanguineous stocks in mice animal models for the study of mania and its subtypes are discussed. Additionally, new experimental alternatives to advance the pathogenesis and pharmacogenetics of mania using animal models are proposed and analyzedJorge Mauricio Cuartas AriasAna María Díaz ZuluagaCarlos López JaramiloUniversidad de San Buenaventuraarticlemodelos animalestrastorno afectivo bipolarknockout y manía.PsychologyBF1-990ENESInternational Journal of Psychological Research, Vol 9, Iss 2 (2016) |
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modelos animales trastorno afectivo bipolar knockout y manía. Psychology BF1-990 |
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modelos animales trastorno afectivo bipolar knockout y manía. Psychology BF1-990 Jorge Mauricio Cuartas Arias Ana María Díaz Zuluaga Carlos López Jaramilo An overview of mice models: a key for understanding subtypes of mania |
| description |
Animal models have been broadly used in the study of pathophysiology and molecular and neurochemical pathways in neuropsychiatric diseases. Different approaches have used both consanguineous and non-consanguineous mice models to model behavioral patterns associated with the maniac spectrum. However, the disadvantages of validating clinical and experimental protocols have hindered the replication of these studies. In this article, the advantages and disadvantages of using consanguineous lines and non-consanguineous stocks in mice animal models for the study of mania and its subtypes are discussed. Additionally, new experimental alternatives to advance the pathogenesis and pharmacogenetics of mania using animal models are proposed and analyzed |
| format |
article |
| author |
Jorge Mauricio Cuartas Arias Ana María Díaz Zuluaga Carlos López Jaramilo |
| author_facet |
Jorge Mauricio Cuartas Arias Ana María Díaz Zuluaga Carlos López Jaramilo |
| author_sort |
Jorge Mauricio Cuartas Arias |
| title |
An overview of mice models: a key for understanding subtypes of mania |
| title_short |
An overview of mice models: a key for understanding subtypes of mania |
| title_full |
An overview of mice models: a key for understanding subtypes of mania |
| title_fullStr |
An overview of mice models: a key for understanding subtypes of mania |
| title_full_unstemmed |
An overview of mice models: a key for understanding subtypes of mania |
| title_sort |
overview of mice models: a key for understanding subtypes of mania |
| publisher |
Universidad de San Buenaventura |
| publishDate |
2016 |
| url |
https://doaj.org/article/8c9b86a715954fd88ad3fbb66f6e89d2 |
| work_keys_str_mv |
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