Wnt/Beta-catenin/Esrrb signalling controls the tissue-scale reorganization and maintenance of the pluripotent lineage during murine embryonic diapause

Wnt/Beta-catenin/Esrrb signalling controls the tissue-scale reorganization and maintenance of the pluripotent lineage during murine embryonic diapause

Embryonic diapause is a state of dormancy with poorly understood mechanisms of embryo intrinsic regulation. Here, the authors show that murine diapause is a dynamic process, where tissue-scale reorganization of the pluripotent lineage is controlled in an autocrine manner by the Wnt/b-catenin/Esrrb s...

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Autores principales: Rui Fan, Yung Su Kim, Jie Wu, Rui Chen, Dagmar Zeuschner, Karina Mildner, Kenjiro Adachi, Guangming Wu, Styliani Galatidou, Jianhua Li, Hans R. Schöler, Sebastian A. Leidel, Ivan Bedzhov
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Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/8ca51a4f837f4e888adc4dfe1fda8fa3
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spelling oai:doaj.org-article:8ca51a4f837f4e888adc4dfe1fda8fa32021-12-02T16:50:03ZWnt/Beta-catenin/Esrrb signalling controls the tissue-scale reorganization and maintenance of the pluripotent lineage during murine embryonic diapause10.1038/s41467-020-19353-02041-1723https://doaj.org/article/8ca51a4f837f4e888adc4dfe1fda8fa32020-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-19353-0https://doaj.org/toc/2041-1723Embryonic diapause is a state of dormancy with poorly understood mechanisms of embryo intrinsic regulation. Here, the authors show that murine diapause is a dynamic process, where tissue-scale reorganization of the pluripotent lineage is controlled in an autocrine manner by the Wnt/b-catenin/Esrrb signalling cascade.Rui FanYung Su KimJie WuRui ChenDagmar ZeuschnerKarina MildnerKenjiro AdachiGuangming WuStyliani GalatidouJianhua LiHans R. SchölerSebastian A. LeidelIvan BedzhovNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Rui Fan
Yung Su Kim
Jie Wu
Rui Chen
Dagmar Zeuschner
Karina Mildner
Kenjiro Adachi
Guangming Wu
Styliani Galatidou
Jianhua Li
Hans R. Schöler
Sebastian A. Leidel
Ivan Bedzhov
Wnt/Beta-catenin/Esrrb signalling controls the tissue-scale reorganization and maintenance of the pluripotent lineage during murine embryonic diapause
description Embryonic diapause is a state of dormancy with poorly understood mechanisms of embryo intrinsic regulation. Here, the authors show that murine diapause is a dynamic process, where tissue-scale reorganization of the pluripotent lineage is controlled in an autocrine manner by the Wnt/b-catenin/Esrrb signalling cascade.
format article
author Rui Fan
Yung Su Kim
Jie Wu
Rui Chen
Dagmar Zeuschner
Karina Mildner
Kenjiro Adachi
Guangming Wu
Styliani Galatidou
Jianhua Li
Hans R. Schöler
Sebastian A. Leidel
Ivan Bedzhov
author_facet Rui Fan
Yung Su Kim
Jie Wu
Rui Chen
Dagmar Zeuschner
Karina Mildner
Kenjiro Adachi
Guangming Wu
Styliani Galatidou
Jianhua Li
Hans R. Schöler
Sebastian A. Leidel
Ivan Bedzhov
author_sort Rui Fan
title Wnt/Beta-catenin/Esrrb signalling controls the tissue-scale reorganization and maintenance of the pluripotent lineage during murine embryonic diapause
title_short Wnt/Beta-catenin/Esrrb signalling controls the tissue-scale reorganization and maintenance of the pluripotent lineage during murine embryonic diapause
title_full Wnt/Beta-catenin/Esrrb signalling controls the tissue-scale reorganization and maintenance of the pluripotent lineage during murine embryonic diapause
title_fullStr Wnt/Beta-catenin/Esrrb signalling controls the tissue-scale reorganization and maintenance of the pluripotent lineage during murine embryonic diapause
title_full_unstemmed Wnt/Beta-catenin/Esrrb signalling controls the tissue-scale reorganization and maintenance of the pluripotent lineage during murine embryonic diapause
title_sort wnt/beta-catenin/esrrb signalling controls the tissue-scale reorganization and maintenance of the pluripotent lineage during murine embryonic diapause
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/8ca51a4f837f4e888adc4dfe1fda8fa3
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