Single-molecule long-read sequencing reveals a conserved intact long RNA profile in sperm

Sperm carry diverse RNAs to the zygote. Here the authors employ single molecule long-read sequencing to distinguish intact RNAs from fragmented RNAs, reporting thousands of intact sperm RNA species conserved in mouse and human sperms.

Guardado en:
Detalles Bibliográficos
Autores principales: Yu H. Sun, Anqi Wang, Chi Song, Goutham Shankar, Rajesh K. Srivastava, Kin Fai Au, Xin Zhiguo Li
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Q
Acceso en línea:https://doaj.org/article/8ca7a5b6c6c14808bfa6cb71b70647fa
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:8ca7a5b6c6c14808bfa6cb71b70647fa
record_format dspace
spelling oai:doaj.org-article:8ca7a5b6c6c14808bfa6cb71b70647fa2021-12-02T15:52:56ZSingle-molecule long-read sequencing reveals a conserved intact long RNA profile in sperm10.1038/s41467-021-21524-62041-1723https://doaj.org/article/8ca7a5b6c6c14808bfa6cb71b70647fa2021-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-21524-6https://doaj.org/toc/2041-1723Sperm carry diverse RNAs to the zygote. Here the authors employ single molecule long-read sequencing to distinguish intact RNAs from fragmented RNAs, reporting thousands of intact sperm RNA species conserved in mouse and human sperms.Yu H. SunAnqi WangChi SongGoutham ShankarRajesh K. SrivastavaKin Fai AuXin Zhiguo LiNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Yu H. Sun
Anqi Wang
Chi Song
Goutham Shankar
Rajesh K. Srivastava
Kin Fai Au
Xin Zhiguo Li
Single-molecule long-read sequencing reveals a conserved intact long RNA profile in sperm
description Sperm carry diverse RNAs to the zygote. Here the authors employ single molecule long-read sequencing to distinguish intact RNAs from fragmented RNAs, reporting thousands of intact sperm RNA species conserved in mouse and human sperms.
format article
author Yu H. Sun
Anqi Wang
Chi Song
Goutham Shankar
Rajesh K. Srivastava
Kin Fai Au
Xin Zhiguo Li
author_facet Yu H. Sun
Anqi Wang
Chi Song
Goutham Shankar
Rajesh K. Srivastava
Kin Fai Au
Xin Zhiguo Li
author_sort Yu H. Sun
title Single-molecule long-read sequencing reveals a conserved intact long RNA profile in sperm
title_short Single-molecule long-read sequencing reveals a conserved intact long RNA profile in sperm
title_full Single-molecule long-read sequencing reveals a conserved intact long RNA profile in sperm
title_fullStr Single-molecule long-read sequencing reveals a conserved intact long RNA profile in sperm
title_full_unstemmed Single-molecule long-read sequencing reveals a conserved intact long RNA profile in sperm
title_sort single-molecule long-read sequencing reveals a conserved intact long rna profile in sperm
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/8ca7a5b6c6c14808bfa6cb71b70647fa
work_keys_str_mv AT yuhsun singlemoleculelongreadsequencingrevealsaconservedintactlongrnaprofileinsperm
AT anqiwang singlemoleculelongreadsequencingrevealsaconservedintactlongrnaprofileinsperm
AT chisong singlemoleculelongreadsequencingrevealsaconservedintactlongrnaprofileinsperm
AT gouthamshankar singlemoleculelongreadsequencingrevealsaconservedintactlongrnaprofileinsperm
AT rajeshksrivastava singlemoleculelongreadsequencingrevealsaconservedintactlongrnaprofileinsperm
AT kinfaiau singlemoleculelongreadsequencingrevealsaconservedintactlongrnaprofileinsperm
AT xinzhiguoli singlemoleculelongreadsequencingrevealsaconservedintactlongrnaprofileinsperm
_version_ 1718385584765927424