Single-molecule long-read sequencing reveals a conserved intact long RNA profile in sperm
Sperm carry diverse RNAs to the zygote. Here the authors employ single molecule long-read sequencing to distinguish intact RNAs from fragmented RNAs, reporting thousands of intact sperm RNA species conserved in mouse and human sperms.
Guardado en:
Autores principales: | , , , , , , |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/8ca7a5b6c6c14808bfa6cb71b70647fa |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
id |
oai:doaj.org-article:8ca7a5b6c6c14808bfa6cb71b70647fa |
---|---|
record_format |
dspace |
spelling |
oai:doaj.org-article:8ca7a5b6c6c14808bfa6cb71b70647fa2021-12-02T15:52:56ZSingle-molecule long-read sequencing reveals a conserved intact long RNA profile in sperm10.1038/s41467-021-21524-62041-1723https://doaj.org/article/8ca7a5b6c6c14808bfa6cb71b70647fa2021-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-21524-6https://doaj.org/toc/2041-1723Sperm carry diverse RNAs to the zygote. Here the authors employ single molecule long-read sequencing to distinguish intact RNAs from fragmented RNAs, reporting thousands of intact sperm RNA species conserved in mouse and human sperms.Yu H. SunAnqi WangChi SongGoutham ShankarRajesh K. SrivastavaKin Fai AuXin Zhiguo LiNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-12 (2021) |
institution |
DOAJ |
collection |
DOAJ |
language |
EN |
topic |
Science Q |
spellingShingle |
Science Q Yu H. Sun Anqi Wang Chi Song Goutham Shankar Rajesh K. Srivastava Kin Fai Au Xin Zhiguo Li Single-molecule long-read sequencing reveals a conserved intact long RNA profile in sperm |
description |
Sperm carry diverse RNAs to the zygote. Here the authors employ single molecule long-read sequencing to distinguish intact RNAs from fragmented RNAs, reporting thousands of intact sperm RNA species conserved in mouse and human sperms. |
format |
article |
author |
Yu H. Sun Anqi Wang Chi Song Goutham Shankar Rajesh K. Srivastava Kin Fai Au Xin Zhiguo Li |
author_facet |
Yu H. Sun Anqi Wang Chi Song Goutham Shankar Rajesh K. Srivastava Kin Fai Au Xin Zhiguo Li |
author_sort |
Yu H. Sun |
title |
Single-molecule long-read sequencing reveals a conserved intact long RNA profile in sperm |
title_short |
Single-molecule long-read sequencing reveals a conserved intact long RNA profile in sperm |
title_full |
Single-molecule long-read sequencing reveals a conserved intact long RNA profile in sperm |
title_fullStr |
Single-molecule long-read sequencing reveals a conserved intact long RNA profile in sperm |
title_full_unstemmed |
Single-molecule long-read sequencing reveals a conserved intact long RNA profile in sperm |
title_sort |
single-molecule long-read sequencing reveals a conserved intact long rna profile in sperm |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/8ca7a5b6c6c14808bfa6cb71b70647fa |
work_keys_str_mv |
AT yuhsun singlemoleculelongreadsequencingrevealsaconservedintactlongrnaprofileinsperm AT anqiwang singlemoleculelongreadsequencingrevealsaconservedintactlongrnaprofileinsperm AT chisong singlemoleculelongreadsequencingrevealsaconservedintactlongrnaprofileinsperm AT gouthamshankar singlemoleculelongreadsequencingrevealsaconservedintactlongrnaprofileinsperm AT rajeshksrivastava singlemoleculelongreadsequencingrevealsaconservedintactlongrnaprofileinsperm AT kinfaiau singlemoleculelongreadsequencingrevealsaconservedintactlongrnaprofileinsperm AT xinzhiguoli singlemoleculelongreadsequencingrevealsaconservedintactlongrnaprofileinsperm |
_version_ |
1718385584765927424 |