Acupuncture in migraine prophylaxis in Czech patients: an open-label randomized controlled trial

Frantisek Musil,1 Jitka Pokladnikova,1,2 Zbysek Pavelek,3 Bo Wang,4 Xin Guan,4 Martin Valis3 1Czech-Chinese Center for Traditional Chinese Medicine, University Hospital Hradec Kralove, Hradec Kralove, Czech Republic; 2Faculty of Pharmacy in Hradec Kralove, Charles University, Hradec Kralove, Czech...

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Autores principales:	Musil F, Pokladnikova J, Pavelek Z, Wang B, Guan X, Valis M
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2018
Materias:	acupuncture effectiveness migraine prophylaxis Traditional Chinese Medicine treatment Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
Acceso en línea:	https://doaj.org/article/8cb4e85f726e454a9f248b7b0ed2137d
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spelling	oai:doaj.org-article:8cb4e85f726e454a9f248b7b0ed2137d2021-12-02T02:53:33ZAcupuncture in migraine prophylaxis in Czech patients: an open-label randomized controlled trial1178-2021https://doaj.org/article/8cb4e85f726e454a9f248b7b0ed2137d2018-05-01T00:00:00Zhttps://www.dovepress.com/acupuncture-in-migraine-prophylaxis-in-czech-patients-an-open-label-ra-peer-reviewed-article-NDThttps://doaj.org/toc/1178-2021Frantisek Musil,1 Jitka Pokladnikova,1,2 Zbysek Pavelek,3 Bo Wang,4 Xin Guan,4 Martin Valis3 1Czech-Chinese Center for Traditional Chinese Medicine, University Hospital Hradec Kralove, Hradec Kralove, Czech Republic; 2Faculty of Pharmacy in Hradec Kralove, Charles University, Hradec Kralove, Czech Republic; 3Department of Neurology, University Hospital Hradec Kralove, Hradec Kralove, Czech Republic; 4Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, People’s Republic of China Background: Adjuvant acupuncture for the symptomatic treatment of migraine reduces the frequency of headaches and may be at least similarly effective to treatment with prophylactic drugs.Methods: This article describes an open-label randomized controlled clinical trial with two groups: the intervention group (n=42) and the waiting-list control group (n=44). This study occurred at the Czech-Chinese Center for Traditional Chinese Medicine at the University Hospital Hradec Kralove between October 2015 and April 2017.Results: After 12 weeks of acupuncture, the number of migraine days was reduced by 5.5 and 2.0 days in the acupuncture and the waiting-list control groups, respectively, with a statistically significant inter-group difference of 2.0 migraine days (95% CI: -4 to -1). A significantly greater reduction in the number of migraine days per 4 weeks was reached at the end of the 6-month follow-up period in the acupuncture vs. control groups (Δ -4.0; 95% CI: -6 to -2). A statistically significant difference was observed in the number of responders to treatment (response defined as at least a 50% reduction in average monthly migraine day frequency) in the acupuncture vs waiting-list control groups (50% vs 27%; p<0.05) at the end of the intervention. A significantly greater percentage of responders to treatment was noted in the intervention vs control groups at the 6-month follow-up (81% vs 36%; p<0.001).Conclusion: Acupuncture can reduce symptoms and medication use, both short term and long term, as an adjuvant treatment in migraine prophylaxis in Czech patients. Keywords: acupuncture, effectiveness, migraine, prophylaxis, Traditional Chinese medicine, treatmentMusil FPokladnikova JPavelek ZWang BGuan XValis MDove Medical PressarticleacupunctureeffectivenessmigraineprophylaxisTraditional Chinese MedicinetreatmentNeurosciences. Biological psychiatry. NeuropsychiatryRC321-571Neurology. Diseases of the nervous systemRC346-429ENNeuropsychiatric Disease and Treatment, Vol Volume 14, Pp 1221-1228 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	acupuncture effectiveness migraine prophylaxis Traditional Chinese Medicine treatment Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
spellingShingle	acupuncture effectiveness migraine prophylaxis Traditional Chinese Medicine treatment Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429 Musil F Pokladnikova J Pavelek Z Wang B Guan X Valis M Acupuncture in migraine prophylaxis in Czech patients: an open-label randomized controlled trial
description	Frantisek Musil,1 Jitka Pokladnikova,1,2 Zbysek Pavelek,3 Bo Wang,4 Xin Guan,4 Martin Valis3 1Czech-Chinese Center for Traditional Chinese Medicine, University Hospital Hradec Kralove, Hradec Kralove, Czech Republic; 2Faculty of Pharmacy in Hradec Kralove, Charles University, Hradec Kralove, Czech Republic; 3Department of Neurology, University Hospital Hradec Kralove, Hradec Kralove, Czech Republic; 4Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, People’s Republic of China Background: Adjuvant acupuncture for the symptomatic treatment of migraine reduces the frequency of headaches and may be at least similarly effective to treatment with prophylactic drugs.Methods: This article describes an open-label randomized controlled clinical trial with two groups: the intervention group (n=42) and the waiting-list control group (n=44). This study occurred at the Czech-Chinese Center for Traditional Chinese Medicine at the University Hospital Hradec Kralove between October 2015 and April 2017.Results: After 12 weeks of acupuncture, the number of migraine days was reduced by 5.5 and 2.0 days in the acupuncture and the waiting-list control groups, respectively, with a statistically significant inter-group difference of 2.0 migraine days (95% CI: -4 to -1). A significantly greater reduction in the number of migraine days per 4 weeks was reached at the end of the 6-month follow-up period in the acupuncture vs. control groups (Δ -4.0; 95% CI: -6 to -2). A statistically significant difference was observed in the number of responders to treatment (response defined as at least a 50% reduction in average monthly migraine day frequency) in the acupuncture vs waiting-list control groups (50% vs 27%; p<0.05) at the end of the intervention. A significantly greater percentage of responders to treatment was noted in the intervention vs control groups at the 6-month follow-up (81% vs 36%; p<0.001).Conclusion: Acupuncture can reduce symptoms and medication use, both short term and long term, as an adjuvant treatment in migraine prophylaxis in Czech patients. Keywords: acupuncture, effectiveness, migraine, prophylaxis, Traditional Chinese medicine, treatment
format	article
author	Musil F Pokladnikova J Pavelek Z Wang B Guan X Valis M
author_facet	Musil F Pokladnikova J Pavelek Z Wang B Guan X Valis M
author_sort	Musil F
title	Acupuncture in migraine prophylaxis in Czech patients: an open-label randomized controlled trial
title_short	Acupuncture in migraine prophylaxis in Czech patients: an open-label randomized controlled trial
title_full	Acupuncture in migraine prophylaxis in Czech patients: an open-label randomized controlled trial
title_fullStr	Acupuncture in migraine prophylaxis in Czech patients: an open-label randomized controlled trial
title_full_unstemmed	Acupuncture in migraine prophylaxis in Czech patients: an open-label randomized controlled trial
title_sort	acupuncture in migraine prophylaxis in czech patients: an open-label randomized controlled trial
publisher	Dove Medical Press
publishDate	2018
url	https://doaj.org/article/8cb4e85f726e454a9f248b7b0ed2137d
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Acupuncture in migraine prophylaxis in Czech patients: an open-label randomized controlled trial

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