CCT8 recovers WTp53-suppressed cell cycle evolution and EMT to promote colorectal cancer progression

Abstract LIM and SH3 protein 1 (LASP1) is a metastasis-related protein reported to enhance tumor progression in colorectal cancer (CRC). However, the underlying mechanism is still elusive. The chaperonin protein containing TCP1 (CCT) is a cellular molecular chaperone complex, which is necessary for...

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Bibliographic Details
Main Authors: Qing Liao, Yun Ren, Yuyi Yang, Xiaohui Zhu, Yunfei Zhi, Yujie Zhang, Yi Chen, Yanqing Ding, Liang Zhao
Format: article
Language:EN
Published: Nature Publishing Group 2021
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Online Access:https://doaj.org/article/8cbca934e7c942eb9cb35a1908afd967
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