Effective Cytotoxic T Lymphocyte Targeting of Persistent HIV-1 during Antiretroviral Therapy Requires Priming of Naive CD8<sup>+</sup> T Cells
ABSTRACT Curing HIV-1 infection will require elimination of persistent cellular reservoirs that harbor latent virus in the face of combination antiretroviral therapy (cART). Proposed immunotherapeutic strategies to cure HIV-1 infection include enhancing lysis of these infected cells by cytotoxic T l...
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Auteurs principaux: | , , , , , , , , , |
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Format: | article |
Langue: | EN |
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American Society for Microbiology
2016
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Accès en ligne: | https://doaj.org/article/8cdc6aa18bb14393afbdb23f988cb829 |
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