Immune responses to a single dose of the AZD1222/Covishield vaccine in health care workers

Here the authors show in a large cohort of healthcare workers that one dose of the AZD1222 vaccine seroconverts 92.9% of vaccinees, irrespective of age and gender, and results in high antibody titers to wild-type SARS-CoV-2 but only low titers to the B.1.351 variant.

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Autores principales: Chandima Jeewandara, Achala Kamaladasa, Pradeep Darshana Pushpakumara, Deshni Jayathilaka, Inoka Sepali Aberathna, Danasekara Rallage Saubhagya Rasikangani Danasekara, Dinuka Guruge, Thushali Ranasinghe, Shashika Dayarathna, Thilagaraj Pathmanathan, Gayasha Somathilake, Panambara Arachchige Deshan Madhusanka, Shyrar Tanussiya Ramu, Tibutius Thanesh Pramanayagam Jayadas, Heshan Kuruppu, Ayesha Wijesinghe, Herath Mudiyanselage Thashmi Nimasha, Dushantha Milroy, Achini Anuja Nandasena, Poththawela Kankanam Gamage Nilanka Sanjeewani, Ruwan Wijayamuni, Sudath Samaraweera, Lisa Schimanski, T. K. Tan, Tao Dong, Graham S. Ogg, Alain Townsend, Gathsaurie Neelika Malavige
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Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/8ce8a0ccd45c48f3a81d8d158056219c
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spelling oai:doaj.org-article:8ce8a0ccd45c48f3a81d8d158056219c2021-12-02T18:46:58ZImmune responses to a single dose of the AZD1222/Covishield vaccine in health care workers10.1038/s41467-021-24579-72041-1723https://doaj.org/article/8ce8a0ccd45c48f3a81d8d158056219c2021-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-24579-7https://doaj.org/toc/2041-1723Here the authors show in a large cohort of healthcare workers that one dose of the AZD1222 vaccine seroconverts 92.9% of vaccinees, irrespective of age and gender, and results in high antibody titers to wild-type SARS-CoV-2 but only low titers to the B.1.351 variant.Chandima JeewandaraAchala KamaladasaPradeep Darshana PushpakumaraDeshni JayathilakaInoka Sepali AberathnaDanasekara Rallage Saubhagya Rasikangani DanasekaraDinuka GurugeThushali RanasingheShashika DayarathnaThilagaraj PathmanathanGayasha SomathilakePanambara Arachchige Deshan MadhusankaShyrar Tanussiya RamuTibutius Thanesh Pramanayagam JayadasHeshan KuruppuAyesha WijesingheHerath Mudiyanselage Thashmi NimashaDushantha MilroyAchini Anuja NandasenaPoththawela Kankanam Gamage Nilanka SanjeewaniRuwan WijayamuniSudath SamaraweeraLisa SchimanskiT. K. TanTao DongGraham S. OggAlain TownsendGathsaurie Neelika MalavigeNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Chandima Jeewandara
Achala Kamaladasa
Pradeep Darshana Pushpakumara
Deshni Jayathilaka
Inoka Sepali Aberathna
Danasekara Rallage Saubhagya Rasikangani Danasekara
Dinuka Guruge
Thushali Ranasinghe
Shashika Dayarathna
Thilagaraj Pathmanathan
Gayasha Somathilake
Panambara Arachchige Deshan Madhusanka
Shyrar Tanussiya Ramu
Tibutius Thanesh Pramanayagam Jayadas
Heshan Kuruppu
Ayesha Wijesinghe
Herath Mudiyanselage Thashmi Nimasha
Dushantha Milroy
Achini Anuja Nandasena
Poththawela Kankanam Gamage Nilanka Sanjeewani
Ruwan Wijayamuni
Sudath Samaraweera
Lisa Schimanski
T. K. Tan
Tao Dong
Graham S. Ogg
Alain Townsend
Gathsaurie Neelika Malavige
Immune responses to a single dose of the AZD1222/Covishield vaccine in health care workers
description Here the authors show in a large cohort of healthcare workers that one dose of the AZD1222 vaccine seroconverts 92.9% of vaccinees, irrespective of age and gender, and results in high antibody titers to wild-type SARS-CoV-2 but only low titers to the B.1.351 variant.
format article
author Chandima Jeewandara
Achala Kamaladasa
Pradeep Darshana Pushpakumara
Deshni Jayathilaka
Inoka Sepali Aberathna
Danasekara Rallage Saubhagya Rasikangani Danasekara
Dinuka Guruge
Thushali Ranasinghe
Shashika Dayarathna
Thilagaraj Pathmanathan
Gayasha Somathilake
Panambara Arachchige Deshan Madhusanka
Shyrar Tanussiya Ramu
Tibutius Thanesh Pramanayagam Jayadas
Heshan Kuruppu
Ayesha Wijesinghe
Herath Mudiyanselage Thashmi Nimasha
Dushantha Milroy
Achini Anuja Nandasena
Poththawela Kankanam Gamage Nilanka Sanjeewani
Ruwan Wijayamuni
Sudath Samaraweera
Lisa Schimanski
T. K. Tan
Tao Dong
Graham S. Ogg
Alain Townsend
Gathsaurie Neelika Malavige
author_facet Chandima Jeewandara
Achala Kamaladasa
Pradeep Darshana Pushpakumara
Deshni Jayathilaka
Inoka Sepali Aberathna
Danasekara Rallage Saubhagya Rasikangani Danasekara
Dinuka Guruge
Thushali Ranasinghe
Shashika Dayarathna
Thilagaraj Pathmanathan
Gayasha Somathilake
Panambara Arachchige Deshan Madhusanka
Shyrar Tanussiya Ramu
Tibutius Thanesh Pramanayagam Jayadas
Heshan Kuruppu
Ayesha Wijesinghe
Herath Mudiyanselage Thashmi Nimasha
Dushantha Milroy
Achini Anuja Nandasena
Poththawela Kankanam Gamage Nilanka Sanjeewani
Ruwan Wijayamuni
Sudath Samaraweera
Lisa Schimanski
T. K. Tan
Tao Dong
Graham S. Ogg
Alain Townsend
Gathsaurie Neelika Malavige
author_sort Chandima Jeewandara
title Immune responses to a single dose of the AZD1222/Covishield vaccine in health care workers
title_short Immune responses to a single dose of the AZD1222/Covishield vaccine in health care workers
title_full Immune responses to a single dose of the AZD1222/Covishield vaccine in health care workers
title_fullStr Immune responses to a single dose of the AZD1222/Covishield vaccine in health care workers
title_full_unstemmed Immune responses to a single dose of the AZD1222/Covishield vaccine in health care workers
title_sort immune responses to a single dose of the azd1222/covishield vaccine in health care workers
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/8ce8a0ccd45c48f3a81d8d158056219c
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