UBB pseudogene 4 encodes functional ubiquitin variants

UBB pseudogene 4 encodes functional ubiquitin variants

Ubiquitin pseudogenes are present in many organisms but whether they encode functional proteins has remained unclear. Here, the authors show that human UBB pseudogene 4 produces ubiquitin variants with amino acid compositions and cellular functions that are distinct from canonical ubiquitin.

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Detalles Bibliográficos
Autores principales: Marie-Line Dubois, Anna Meller, Sondos Samandi, Mylène Brunelle, Julie Frion, Marie A. Brunet, Amanda Toupin, Maxime C. Beaudoin, Jean-François Jacques, Dominique Lévesque, Michelle S. Scott, Pierre Lavigne, Xavier Roucou, François-Michel Boisvert
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/8ce974c41a46437d9f1dfb98b66ade74
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