UBB pseudogene 4 encodes functional ubiquitin variants
Ubiquitin pseudogenes are present in many organisms but whether they encode functional proteins has remained unclear. Here, the authors show that human UBB pseudogene 4 produces ubiquitin variants with amino acid compositions and cellular functions that are distinct from canonical ubiquitin.
Saved in:
Main Authors: | Marie-Line Dubois, Anna Meller, Sondos Samandi, Mylène Brunelle, Julie Frion, Marie A. Brunet, Amanda Toupin, Maxime C. Beaudoin, Jean-François Jacques, Dominique Lévesque, Michelle S. Scott, Pierre Lavigne, Xavier Roucou, François-Michel Boisvert |
---|---|
Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2020
|
Subjects: | |
Online Access: | https://doaj.org/article/8ce974c41a46437d9f1dfb98b66ade74 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Protein interaction network of alternatively spliced NudCD1 isoforms
by: Patrick Asselin-Mullen, et al.
Published: (2017) -
Structural characterization and duplication modes of pseudogenes in plants
by: Flavia Mascagni, et al.
Published: (2021) -
Genome-wide survey for biologically functional pseudogenes.
by: Orjan Svensson, et al.
Published: (2006) -
Transcriptional activity and strain-specific history of mouse pseudogenes
by: Cristina Sisu, et al.
Published: (2020) -
Accelerated pseudogenization on the neo-X chromosome in Drosophila miranda
by: Masafumi Nozawa, et al.
Published: (2016)