Structure and Peculiarities of a Clinical Course of Tick-Borne Infections in Children of the Irkutsk Region

At present there are few studies generalizing the clinical picture of infections, transmitted by Ixodid ticks, in children population. Tick-borne viral encephalitis is still one of the important natural focal infections and accounts for up to 27 % among other tick-borne infections.The aim of the stu...

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Autores principales:	Ekaterina D. Kazantseva, Andrey Yu. Kazantsev, Alla G. Petrova, Tatiana A. Kirillova
Formato:	article
Lenguaje:	RU
Publicado:	Scientific Сentre for Family Health and Human Reproduction Problems 2019
Materias:	tick-borne viral encephalitis ixodid tick-borne borreliosis tick-borne rickettsiosis vaccine prophylaxis Science Q
Acceso en línea:	https://doaj.org/article/8cea1152d2c44705b3f2ad779e63ee39
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spelling	oai:doaj.org-article:8cea1152d2c44705b3f2ad779e63ee392021-11-23T06:14:42ZStructure and Peculiarities of a Clinical Course of Tick-Borne Infections in Children of the Irkutsk Region2541-94202587-959610.29413/ABS.2019-4.1.4https://doaj.org/article/8cea1152d2c44705b3f2ad779e63ee392019-04-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/1974https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596At present there are few studies generalizing the clinical picture of infections, transmitted by Ixodid ticks, in children population. Tick-borne viral encephalitis is still one of the important natural focal infections and accounts for up to 27 % among other tick-borne infections.The aim of the study was to determine the structure and features of the clinical course of tick infections in children of the Irkutsk region.Materials and methods. We conducted a retrospective analysis of 58 cases over three-year period from 2015 to 2017 of children aged 1 to 18 years diagnosed with tick-borne viral encephalitis (TVE), ixodid tick-borne borreliosis (ITB), tick-borne rickettsiosis (TR) according to the data of Irkutsk Regional Infectious Clinical Hospital.Results and discussion. Among tick-borne infections, TVE was found in 43 % of cases, ITB – in 27.5 %, TR – in 29.5 %, there was one case of mixed infection: TVE + tick-borne typhus in North Asia. In TVE, feverish form was found in 40 % of cases, meningeal form – in 36 %, meningoencephalitic form – in 20 %, polyradiculonevritic form – in 4 %. Medium severity was observed in 56 % of cases, severe – in 28 %. In ITB, non-erythematous form was revealed in 62.5 % of cases, erythematous – in 12.5 %. Clinical and epidemiological TR was registered in 18 % of cases. In patients with TVE recovery was observed in 84 %, however, there were 4 % of neurological complications. With the diagnosis of ITB and TR, almost all children were discharged in a satisfactory condition. No deaths were reported within 3 years. According to the medical history: only 1 child was vaccinated against TVE, 2 children underwent seroprevention; ticks, who bit 4 patients, were studied. Medical history showed that 57 % of children had tick bites, and 7 % of cases associated the disease with consumption of non-boiled goat or cow milk. Residents of Irkutsk, Angarsk and Shelekhov comprised 47 %, residents of the Irkutsk region – 53 %. The most common localization of bites is the head and neck.Conclusion. There is a low public commitment to the vaccine prevention of tick-borne infections. Therefore, it is necessary to promote both specific and non-specific prevention of tick-borne encephalitis among children of the Irkutsk region.Ekaterina D. KazantsevaAndrey Yu. KazantsevAlla G. PetrovaTatiana A. KirillovaScientific Сentre for Family Health and Human Reproduction Problemsarticletick-borne viral encephalitisixodid tick-borne borreliosistick-borne rickettsiosisvaccine prophylaxisScienceQRUActa Biomedica Scientifica, Vol 4, Iss 1, Pp 26-30 (2019)
institution	DOAJ
collection	DOAJ
language	RU
topic	tick-borne viral encephalitis ixodid tick-borne borreliosis tick-borne rickettsiosis vaccine prophylaxis Science Q
spellingShingle	tick-borne viral encephalitis ixodid tick-borne borreliosis tick-borne rickettsiosis vaccine prophylaxis Science Q Ekaterina D. Kazantseva Andrey Yu. Kazantsev Alla G. Petrova Tatiana A. Kirillova Structure and Peculiarities of a Clinical Course of Tick-Borne Infections in Children of the Irkutsk Region
description	At present there are few studies generalizing the clinical picture of infections, transmitted by Ixodid ticks, in children population. Tick-borne viral encephalitis is still one of the important natural focal infections and accounts for up to 27 % among other tick-borne infections.The aim of the study was to determine the structure and features of the clinical course of tick infections in children of the Irkutsk region.Materials and methods. We conducted a retrospective analysis of 58 cases over three-year period from 2015 to 2017 of children aged 1 to 18 years diagnosed with tick-borne viral encephalitis (TVE), ixodid tick-borne borreliosis (ITB), tick-borne rickettsiosis (TR) according to the data of Irkutsk Regional Infectious Clinical Hospital.Results and discussion. Among tick-borne infections, TVE was found in 43 % of cases, ITB – in 27.5 %, TR – in 29.5 %, there was one case of mixed infection: TVE + tick-borne typhus in North Asia. In TVE, feverish form was found in 40 % of cases, meningeal form – in 36 %, meningoencephalitic form – in 20 %, polyradiculonevritic form – in 4 %. Medium severity was observed in 56 % of cases, severe – in 28 %. In ITB, non-erythematous form was revealed in 62.5 % of cases, erythematous – in 12.5 %. Clinical and epidemiological TR was registered in 18 % of cases. In patients with TVE recovery was observed in 84 %, however, there were 4 % of neurological complications. With the diagnosis of ITB and TR, almost all children were discharged in a satisfactory condition. No deaths were reported within 3 years. According to the medical history: only 1 child was vaccinated against TVE, 2 children underwent seroprevention; ticks, who bit 4 patients, were studied. Medical history showed that 57 % of children had tick bites, and 7 % of cases associated the disease with consumption of non-boiled goat or cow milk. Residents of Irkutsk, Angarsk and Shelekhov comprised 47 %, residents of the Irkutsk region – 53 %. The most common localization of bites is the head and neck.Conclusion. There is a low public commitment to the vaccine prevention of tick-borne infections. Therefore, it is necessary to promote both specific and non-specific prevention of tick-borne encephalitis among children of the Irkutsk region.
format	article
author	Ekaterina D. Kazantseva Andrey Yu. Kazantsev Alla G. Petrova Tatiana A. Kirillova
author_facet	Ekaterina D. Kazantseva Andrey Yu. Kazantsev Alla G. Petrova Tatiana A. Kirillova
author_sort	Ekaterina D. Kazantseva
title	Structure and Peculiarities of a Clinical Course of Tick-Borne Infections in Children of the Irkutsk Region
title_short	Structure and Peculiarities of a Clinical Course of Tick-Borne Infections in Children of the Irkutsk Region
title_full	Structure and Peculiarities of a Clinical Course of Tick-Borne Infections in Children of the Irkutsk Region
title_fullStr	Structure and Peculiarities of a Clinical Course of Tick-Borne Infections in Children of the Irkutsk Region
title_full_unstemmed	Structure and Peculiarities of a Clinical Course of Tick-Borne Infections in Children of the Irkutsk Region
title_sort	structure and peculiarities of a clinical course of tick-borne infections in children of the irkutsk region
publisher	Scientific Сentre for Family Health and Human Reproduction Problems
publishDate	2019
url	https://doaj.org/article/8cea1152d2c44705b3f2ad779e63ee39
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Structure and Peculiarities of a Clinical Course of Tick-Borne Infections in Children of the Irkutsk Region

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