Epithelial Remodeling Following Phacoemulsification in Diabetic Patients Using Anterior-Segment Optical Coherence Tomography: A Comparative Study

Hany Elmekawey, Magda Abdelaziz, Mohamed El Baradey, Mohamed Kotb Ophthalmology, Kasr Alainy Faculty of Medicine, Cairo University, Cairo, EgyptCorrespondence: Mohamed Kotb 3 Montaser Housing, Elharam, Giza, EgyptTel +20 2 12263-56283Email d_msabry@yahoo.comPurpose: To compare the effect of phacoemu...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Elmekawey H, Abdelaziz M, El Baradey M, Kotb M
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2020
Materias:	cornea epithelial thickness phacoemulsification diabetics ocular coherence tomography Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/8cebe10db3bf416da8c2cffa3603aae4
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:8cebe10db3bf416da8c2cffa3603aae4
record_format	dspace
spelling	oai:doaj.org-article:8cebe10db3bf416da8c2cffa3603aae42021-12-02T10:26:13ZEpithelial Remodeling Following Phacoemulsification in Diabetic Patients Using Anterior-Segment Optical Coherence Tomography: A Comparative Study1177-5483https://doaj.org/article/8cebe10db3bf416da8c2cffa3603aae42020-08-01T00:00:00Zhttps://www.dovepress.com/epithelial-remodeling-following-phacoemulsification-in-diabetic-patien-peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483Hany Elmekawey, Magda Abdelaziz, Mohamed El Baradey, Mohamed Kotb Ophthalmology, Kasr Alainy Faculty of Medicine, Cairo University, Cairo, EgyptCorrespondence: Mohamed Kotb 3 Montaser Housing, Elharam, Giza, EgyptTel +20 2 12263-56283Email d_msabry@yahoo.comPurpose: To compare the effect of phacoemulsification on corneal epithelial thickness in diabetic and nondiabetic cataract patients.Methods: Fifty eyes with cataracts were enrolled in a prospective comparative interventional study. They were divided into two groups: group A (diabetics) and group B (nondiabetics) and underwent uneventful phacoemulsification. Epithelial thickness was assessed in the central, paracentral, and peripheral cornea on the first day and at 1 week, 1 month, and 3 months postoperatively using spectral-domain ocular coherence tomography.Results: A significant increase in the first-day postoperative central epithelial thickness was noticed in both groups (57.16± 3.5 μm and 55.96± 2.81 μm in groups A and B, respectively), with increased baseline epithelial thickness of 3.8± 2.1 μm and 3.4± 2.14 μm in groups A and B, respectively (P< 0.001). A significant decrease in epithelial thickness was noticed in both groups after 1 week (− 2.40± 3.1 μm and − 2.76± 2.71 μm in group A and B, respectively). No further significant change was noticed in the nondiabetic group at 1 month; however, significant reductions in for central epithelial thickness were found in the diabetic group up to the first month (− 0.80± 1.9 μm, P=0.05). Central corneal thickness followed the same pattern of change as the epithelium. A nonsignificant delay in visual acuity improvement was noticed in diabetic patients.Conclusion: Phacoemulsification induces a temporary increase in corneal and epithelial thickness that should resolve by the first week postoperatively. However, diabetic patients had slower epithelial recovery that took up to 1 month, which could be reflected in delayed visual recovery with no effect on the final visual outcome.Keywords: cornea, epithelial thickness, phacoemulsification, diabetics, ocular coherence tomographyElmekawey HAbdelaziz MEl Baradey MKotb MDove Medical Pressarticlecorneaepithelial thicknessphacoemulsificationdiabeticsocular coherence tomographyOphthalmologyRE1-994ENClinical Ophthalmology, Vol Volume 14, Pp 2515-2523 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	cornea epithelial thickness phacoemulsification diabetics ocular coherence tomography Ophthalmology RE1-994
spellingShingle	cornea epithelial thickness phacoemulsification diabetics ocular coherence tomography Ophthalmology RE1-994 Elmekawey H Abdelaziz M El Baradey M Kotb M Epithelial Remodeling Following Phacoemulsification in Diabetic Patients Using Anterior-Segment Optical Coherence Tomography: A Comparative Study
description	Hany Elmekawey, Magda Abdelaziz, Mohamed El Baradey, Mohamed Kotb Ophthalmology, Kasr Alainy Faculty of Medicine, Cairo University, Cairo, EgyptCorrespondence: Mohamed Kotb 3 Montaser Housing, Elharam, Giza, EgyptTel +20 2 12263-56283Email d_msabry@yahoo.comPurpose: To compare the effect of phacoemulsification on corneal epithelial thickness in diabetic and nondiabetic cataract patients.Methods: Fifty eyes with cataracts were enrolled in a prospective comparative interventional study. They were divided into two groups: group A (diabetics) and group B (nondiabetics) and underwent uneventful phacoemulsification. Epithelial thickness was assessed in the central, paracentral, and peripheral cornea on the first day and at 1 week, 1 month, and 3 months postoperatively using spectral-domain ocular coherence tomography.Results: A significant increase in the first-day postoperative central epithelial thickness was noticed in both groups (57.16± 3.5 μm and 55.96± 2.81 μm in groups A and B, respectively), with increased baseline epithelial thickness of 3.8± 2.1 μm and 3.4± 2.14 μm in groups A and B, respectively (P< 0.001). A significant decrease in epithelial thickness was noticed in both groups after 1 week (− 2.40± 3.1 μm and − 2.76± 2.71 μm in group A and B, respectively). No further significant change was noticed in the nondiabetic group at 1 month; however, significant reductions in for central epithelial thickness were found in the diabetic group up to the first month (− 0.80± 1.9 μm, P=0.05). Central corneal thickness followed the same pattern of change as the epithelium. A nonsignificant delay in visual acuity improvement was noticed in diabetic patients.Conclusion: Phacoemulsification induces a temporary increase in corneal and epithelial thickness that should resolve by the first week postoperatively. However, diabetic patients had slower epithelial recovery that took up to 1 month, which could be reflected in delayed visual recovery with no effect on the final visual outcome.Keywords: cornea, epithelial thickness, phacoemulsification, diabetics, ocular coherence tomography
format	article
author	Elmekawey H Abdelaziz M El Baradey M Kotb M
author_facet	Elmekawey H Abdelaziz M El Baradey M Kotb M
author_sort	Elmekawey H
title	Epithelial Remodeling Following Phacoemulsification in Diabetic Patients Using Anterior-Segment Optical Coherence Tomography: A Comparative Study
title_short	Epithelial Remodeling Following Phacoemulsification in Diabetic Patients Using Anterior-Segment Optical Coherence Tomography: A Comparative Study
title_full	Epithelial Remodeling Following Phacoemulsification in Diabetic Patients Using Anterior-Segment Optical Coherence Tomography: A Comparative Study
title_fullStr	Epithelial Remodeling Following Phacoemulsification in Diabetic Patients Using Anterior-Segment Optical Coherence Tomography: A Comparative Study
title_full_unstemmed	Epithelial Remodeling Following Phacoemulsification in Diabetic Patients Using Anterior-Segment Optical Coherence Tomography: A Comparative Study
title_sort	epithelial remodeling following phacoemulsification in diabetic patients using anterior-segment optical coherence tomography: a comparative study
publisher	Dove Medical Press
publishDate	2020
url	https://doaj.org/article/8cebe10db3bf416da8c2cffa3603aae4
work_keys_str_mv	AT elmekaweyh epithelialremodelingfollowingphacoemulsificationindiabeticpatientsusinganteriorsegmentopticalcoherencetomographyacomparativestudy AT abdelazizm epithelialremodelingfollowingphacoemulsificationindiabeticpatientsusinganteriorsegmentopticalcoherencetomographyacomparativestudy AT elbaradeym epithelialremodelingfollowingphacoemulsificationindiabeticpatientsusinganteriorsegmentopticalcoherencetomographyacomparativestudy AT kotbm epithelialremodelingfollowingphacoemulsificationindiabeticpatientsusinganteriorsegmentopticalcoherencetomographyacomparativestudy
_version_	1718397237338308608

Epithelial Remodeling Following Phacoemulsification in Diabetic Patients Using Anterior-Segment Optical Coherence Tomography: A Comparative Study

Ejemplares similares