Continuous decrease in serum brain-derived neurotrophic factor (BDNF) levels in a neuropsychiatric syndrome of systemic lupus erythematosus patient with organic brain changes
Atsuko Ikenouchi-Sugita, Reiji Yoshimura, Nobuhisa Ueda, Yuki Kodama, Wakako Umene-Nakano, Jun NakamuraDepartment of Psychiatry, School of Medicine, University of Occupational and Environmental Health, Iseigaoka, Yahatanishi-ku, Kitakyushu, Fukuoka, JapanAbstract: In the present study, the authors r...
Guardado en:
Autores principales: | , , , , , |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Dove Medical Press
2008
|
Materias: | |
Acceso en línea: | https://doaj.org/article/8cf028a391c84ae1b14f098c736c39df |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
id |
oai:doaj.org-article:8cf028a391c84ae1b14f098c736c39df |
---|---|
record_format |
dspace |
spelling |
oai:doaj.org-article:8cf028a391c84ae1b14f098c736c39df2021-12-02T07:07:32ZContinuous decrease in serum brain-derived neurotrophic factor (BDNF) levels in a neuropsychiatric syndrome of systemic lupus erythematosus patient with organic brain changes1176-63281178-2021https://doaj.org/article/8cf028a391c84ae1b14f098c736c39df2008-10-01T00:00:00Zhttp://www.dovepress.com/continuous-decrease-in-serum-brain-derived-neurotrophic-factor-bdnf-le-a2472https://doaj.org/toc/1176-6328https://doaj.org/toc/1178-2021Atsuko Ikenouchi-Sugita, Reiji Yoshimura, Nobuhisa Ueda, Yuki Kodama, Wakako Umene-Nakano, Jun NakamuraDepartment of Psychiatry, School of Medicine, University of Occupational and Environmental Health, Iseigaoka, Yahatanishi-ku, Kitakyushu, Fukuoka, JapanAbstract: In the present study, the authors reported on a case in neuropsychiatric syndromes of systemic lupus erythematosus (NPSLE) with irreversible organic brain changes. The authors also longitudinally investigated serum brain-derived neurotrophic factor (BDNF) levels in the patient. We found that serum BDNF levels in the NPSLE patient with irreversible organic brain change were consistently low, independent of the severity of psychiatric symptoms. Thus, the longitudinal measurement of serum BDNF levels might be useful in predicting the prognosis of NPSLE.Keywords: brain-derived neurotrophic factor; neuropsychiatric syndrome of systemic lupus erythematosus; organic brain change Atsuko Ikenouchi-SugitaReiji YoshimuraNobuhisa UedaYuki KodamaWakako Umene-NakanoJun NakamuraDove Medical PressarticleNeurosciences. Biological psychiatry. NeuropsychiatryRC321-571Neurology. Diseases of the nervous systemRC346-429ENNeuropsychiatric Disease and Treatment, Vol 2008, Iss Issue 6, Pp 1277-1281 (2008) |
institution |
DOAJ |
collection |
DOAJ |
language |
EN |
topic |
Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429 |
spellingShingle |
Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429 Atsuko Ikenouchi-Sugita Reiji Yoshimura Nobuhisa Ueda Yuki Kodama Wakako Umene-Nakano Jun Nakamura Continuous decrease in serum brain-derived neurotrophic factor (BDNF) levels in a neuropsychiatric syndrome of systemic lupus erythematosus patient with organic brain changes |
description |
Atsuko Ikenouchi-Sugita, Reiji Yoshimura, Nobuhisa Ueda, Yuki Kodama, Wakako Umene-Nakano, Jun NakamuraDepartment of Psychiatry, School of Medicine, University of Occupational and Environmental Health, Iseigaoka, Yahatanishi-ku, Kitakyushu, Fukuoka, JapanAbstract: In the present study, the authors reported on a case in neuropsychiatric syndromes of systemic lupus erythematosus (NPSLE) with irreversible organic brain changes. The authors also longitudinally investigated serum brain-derived neurotrophic factor (BDNF) levels in the patient. We found that serum BDNF levels in the NPSLE patient with irreversible organic brain change were consistently low, independent of the severity of psychiatric symptoms. Thus, the longitudinal measurement of serum BDNF levels might be useful in predicting the prognosis of NPSLE.Keywords: brain-derived neurotrophic factor; neuropsychiatric syndrome of systemic lupus erythematosus; organic brain change |
format |
article |
author |
Atsuko Ikenouchi-Sugita Reiji Yoshimura Nobuhisa Ueda Yuki Kodama Wakako Umene-Nakano Jun Nakamura |
author_facet |
Atsuko Ikenouchi-Sugita Reiji Yoshimura Nobuhisa Ueda Yuki Kodama Wakako Umene-Nakano Jun Nakamura |
author_sort |
Atsuko Ikenouchi-Sugita |
title |
Continuous decrease in serum brain-derived neurotrophic factor (BDNF) levels in a neuropsychiatric syndrome of systemic lupus erythematosus patient with organic brain changes |
title_short |
Continuous decrease in serum brain-derived neurotrophic factor (BDNF) levels in a neuropsychiatric syndrome of systemic lupus erythematosus patient with organic brain changes |
title_full |
Continuous decrease in serum brain-derived neurotrophic factor (BDNF) levels in a neuropsychiatric syndrome of systemic lupus erythematosus patient with organic brain changes |
title_fullStr |
Continuous decrease in serum brain-derived neurotrophic factor (BDNF) levels in a neuropsychiatric syndrome of systemic lupus erythematosus patient with organic brain changes |
title_full_unstemmed |
Continuous decrease in serum brain-derived neurotrophic factor (BDNF) levels in a neuropsychiatric syndrome of systemic lupus erythematosus patient with organic brain changes |
title_sort |
continuous decrease in serum brain-derived neurotrophic factor (bdnf) levels in a neuropsychiatric syndrome of systemic lupus erythematosus patient with organic brain changes |
publisher |
Dove Medical Press |
publishDate |
2008 |
url |
https://doaj.org/article/8cf028a391c84ae1b14f098c736c39df |
work_keys_str_mv |
AT atsukoikenouchisugita continuousdecreaseinserumbrainderivedneurotrophicfactorbdnflevelsinaneuropsychiatricsyndromeofsystemiclupuserythematosuspatientwithorganicbrainchanges AT reijiyoshimura continuousdecreaseinserumbrainderivedneurotrophicfactorbdnflevelsinaneuropsychiatricsyndromeofsystemiclupuserythematosuspatientwithorganicbrainchanges AT nobuhisaueda continuousdecreaseinserumbrainderivedneurotrophicfactorbdnflevelsinaneuropsychiatricsyndromeofsystemiclupuserythematosuspatientwithorganicbrainchanges AT yukikodama continuousdecreaseinserumbrainderivedneurotrophicfactorbdnflevelsinaneuropsychiatricsyndromeofsystemiclupuserythematosuspatientwithorganicbrainchanges AT wakakoumenenakano continuousdecreaseinserumbrainderivedneurotrophicfactorbdnflevelsinaneuropsychiatricsyndromeofsystemiclupuserythematosuspatientwithorganicbrainchanges AT junnakamura continuousdecreaseinserumbrainderivedneurotrophicfactorbdnflevelsinaneuropsychiatricsyndromeofsystemiclupuserythematosuspatientwithorganicbrainchanges |
_version_ |
1718399587736092672 |