The endosomal Q-SNARE, Syntaxin 7, defines a rapidly replenishing synaptic vesicle recycling pool in hippocampal neurons
Yasunori Mori et al. find that a subset of neurotransmitter-bearing synaptic vesicles are marked for release by the endosomal Q-SNARE protein Stx7. They show that Stx7 function is necessary for the rapid replenishment of synaptic vesicles that is needed to sustain synaptic transmission during high-f...
Guardado en:
Autores principales: | , , , |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/8cf84947d7404ce99a4bd2a13623511d |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
id |
oai:doaj.org-article:8cf84947d7404ce99a4bd2a13623511d |
---|---|
record_format |
dspace |
spelling |
oai:doaj.org-article:8cf84947d7404ce99a4bd2a13623511d2021-12-02T18:51:45ZThe endosomal Q-SNARE, Syntaxin 7, defines a rapidly replenishing synaptic vesicle recycling pool in hippocampal neurons10.1038/s42003-021-02512-42399-3642https://doaj.org/article/8cf84947d7404ce99a4bd2a13623511d2021-08-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02512-4https://doaj.org/toc/2399-3642Yasunori Mori et al. find that a subset of neurotransmitter-bearing synaptic vesicles are marked for release by the endosomal Q-SNARE protein Stx7. They show that Stx7 function is necessary for the rapid replenishment of synaptic vesicles that is needed to sustain synaptic transmission during high-frequency stimulation.Yasunori MoriKoh-ichiro TakenakaYugo FukazawaShigeo TakamoriNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-13 (2021) |
institution |
DOAJ |
collection |
DOAJ |
language |
EN |
topic |
Biology (General) QH301-705.5 |
spellingShingle |
Biology (General) QH301-705.5 Yasunori Mori Koh-ichiro Takenaka Yugo Fukazawa Shigeo Takamori The endosomal Q-SNARE, Syntaxin 7, defines a rapidly replenishing synaptic vesicle recycling pool in hippocampal neurons |
description |
Yasunori Mori et al. find that a subset of neurotransmitter-bearing synaptic vesicles are marked for release by the endosomal Q-SNARE protein Stx7. They show that Stx7 function is necessary for the rapid replenishment of synaptic vesicles that is needed to sustain synaptic transmission during high-frequency stimulation. |
format |
article |
author |
Yasunori Mori Koh-ichiro Takenaka Yugo Fukazawa Shigeo Takamori |
author_facet |
Yasunori Mori Koh-ichiro Takenaka Yugo Fukazawa Shigeo Takamori |
author_sort |
Yasunori Mori |
title |
The endosomal Q-SNARE, Syntaxin 7, defines a rapidly replenishing synaptic vesicle recycling pool in hippocampal neurons |
title_short |
The endosomal Q-SNARE, Syntaxin 7, defines a rapidly replenishing synaptic vesicle recycling pool in hippocampal neurons |
title_full |
The endosomal Q-SNARE, Syntaxin 7, defines a rapidly replenishing synaptic vesicle recycling pool in hippocampal neurons |
title_fullStr |
The endosomal Q-SNARE, Syntaxin 7, defines a rapidly replenishing synaptic vesicle recycling pool in hippocampal neurons |
title_full_unstemmed |
The endosomal Q-SNARE, Syntaxin 7, defines a rapidly replenishing synaptic vesicle recycling pool in hippocampal neurons |
title_sort |
endosomal q-snare, syntaxin 7, defines a rapidly replenishing synaptic vesicle recycling pool in hippocampal neurons |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/8cf84947d7404ce99a4bd2a13623511d |
work_keys_str_mv |
AT yasunorimori theendosomalqsnaresyntaxin7definesarapidlyreplenishingsynapticvesiclerecyclingpoolinhippocampalneurons AT kohichirotakenaka theendosomalqsnaresyntaxin7definesarapidlyreplenishingsynapticvesiclerecyclingpoolinhippocampalneurons AT yugofukazawa theendosomalqsnaresyntaxin7definesarapidlyreplenishingsynapticvesiclerecyclingpoolinhippocampalneurons AT shigeotakamori theendosomalqsnaresyntaxin7definesarapidlyreplenishingsynapticvesiclerecyclingpoolinhippocampalneurons AT yasunorimori endosomalqsnaresyntaxin7definesarapidlyreplenishingsynapticvesiclerecyclingpoolinhippocampalneurons AT kohichirotakenaka endosomalqsnaresyntaxin7definesarapidlyreplenishingsynapticvesiclerecyclingpoolinhippocampalneurons AT yugofukazawa endosomalqsnaresyntaxin7definesarapidlyreplenishingsynapticvesiclerecyclingpoolinhippocampalneurons AT shigeotakamori endosomalqsnaresyntaxin7definesarapidlyreplenishingsynapticvesiclerecyclingpoolinhippocampalneurons |
_version_ |
1718377395926335488 |