DIAGNOSTIC ACCURACY OF CONTRAST ENHANCED COMPUTED TOMOGRAPHY IN STAGING OF COLORECTAL CARCINOMA

Objective: To determine the diagnostic accuracy of CT scan in staging of colorectal carcinoma among biopsy proven patients of colorectal carcinoma by taking histopathological finding as gold standard. Study Design: Cross-sectional validation study. Place and Duration of Study: Combined Military H...

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Autores principales: Nasira Sultana, Sumayya Khan, Salah Ud Din Baloch
Formato: article
Lenguaje:EN
Publicado: Army Medical College Rawalpindi 2018
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Acceso en línea:https://doaj.org/article/8cfabf75514a49cdaeec4be864f309e8
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spelling oai:doaj.org-article:8cfabf75514a49cdaeec4be864f309e82021-12-01T02:57:16ZDIAGNOSTIC ACCURACY OF CONTRAST ENHANCED COMPUTED TOMOGRAPHY IN STAGING OF COLORECTAL CARCINOMA0030-96482411-8842https://doaj.org/article/8cfabf75514a49cdaeec4be864f309e82018-10-01T00:00:00Zhttps://www.pafmj.org/index.php/PAFMJ/article/view/2239/1942https://doaj.org/toc/0030-9648https://doaj.org/toc/2411-8842Objective: To determine the diagnostic accuracy of CT scan in staging of colorectal carcinoma among biopsy proven patients of colorectal carcinoma by taking histopathological finding as gold standard. Study Design: Cross-sectional validation study. Place and Duration of Study: Combined Military Hospital Rawalpindi, Six months, from Jul 2015 to Dec 2015. Material and Methods: A total of 176 cases of 15-70 years of age, diagnosed of colorectal carcinoma oncolonoscopic biopsy, were included in the study. Patients with previous malignancies other than colorectal carcinoma, allergy to the contrast agent and pregnant patients were excluded from the study. All the patients then underwent CT scan for detection of the stage of cancer. After surgery, histopathology of the resected specimen was compared with the findings on CT scan. Results: Mean age was 50.27 ± 14.50 years. Out of these 176 patients, 113 (64.20%) were male and 63 (35.80%) were females with ratio of 1.8:1. Among CT positive, 80 were true positive while 11 were false positive. Among, CT negative patients, 12 were false negative while 73 were true negative. Overall sensitivity, specificity, positive predictive value, negative predictive value and diagnostic accuracy of CT in staging colorectal carcinoma taking histopathology as gold standard was 87.91%, 85.88%, 86.96%, 86.90% and 86.93% respectively. Conclusion: This study concluded that CT scan is a highly sensitive and accurate modality for pre-operative detection of stage of colorectal carcinoma.Nasira SultanaSumayya KhanSalah Ud Din BalochArmy Medical College Rawalpindiarticlecolorectal cancerimaging modalitysensitivityMedicineRMedicine (General)R5-920ENPakistan Armed Forces Medical Journal, Vol 68, Iss 5, Pp 1076-1081 (2018)
institution DOAJ
collection DOAJ
language EN
topic colorectal cancer
imaging modality
sensitivity
Medicine
R
Medicine (General)
R5-920
spellingShingle colorectal cancer
imaging modality
sensitivity
Medicine
R
Medicine (General)
R5-920
Nasira Sultana
Sumayya Khan
Salah Ud Din Baloch
DIAGNOSTIC ACCURACY OF CONTRAST ENHANCED COMPUTED TOMOGRAPHY IN STAGING OF COLORECTAL CARCINOMA
description Objective: To determine the diagnostic accuracy of CT scan in staging of colorectal carcinoma among biopsy proven patients of colorectal carcinoma by taking histopathological finding as gold standard. Study Design: Cross-sectional validation study. Place and Duration of Study: Combined Military Hospital Rawalpindi, Six months, from Jul 2015 to Dec 2015. Material and Methods: A total of 176 cases of 15-70 years of age, diagnosed of colorectal carcinoma oncolonoscopic biopsy, were included in the study. Patients with previous malignancies other than colorectal carcinoma, allergy to the contrast agent and pregnant patients were excluded from the study. All the patients then underwent CT scan for detection of the stage of cancer. After surgery, histopathology of the resected specimen was compared with the findings on CT scan. Results: Mean age was 50.27 ± 14.50 years. Out of these 176 patients, 113 (64.20%) were male and 63 (35.80%) were females with ratio of 1.8:1. Among CT positive, 80 were true positive while 11 were false positive. Among, CT negative patients, 12 were false negative while 73 were true negative. Overall sensitivity, specificity, positive predictive value, negative predictive value and diagnostic accuracy of CT in staging colorectal carcinoma taking histopathology as gold standard was 87.91%, 85.88%, 86.96%, 86.90% and 86.93% respectively. Conclusion: This study concluded that CT scan is a highly sensitive and accurate modality for pre-operative detection of stage of colorectal carcinoma.
format article
author Nasira Sultana
Sumayya Khan
Salah Ud Din Baloch
author_facet Nasira Sultana
Sumayya Khan
Salah Ud Din Baloch
author_sort Nasira Sultana
title DIAGNOSTIC ACCURACY OF CONTRAST ENHANCED COMPUTED TOMOGRAPHY IN STAGING OF COLORECTAL CARCINOMA
title_short DIAGNOSTIC ACCURACY OF CONTRAST ENHANCED COMPUTED TOMOGRAPHY IN STAGING OF COLORECTAL CARCINOMA
title_full DIAGNOSTIC ACCURACY OF CONTRAST ENHANCED COMPUTED TOMOGRAPHY IN STAGING OF COLORECTAL CARCINOMA
title_fullStr DIAGNOSTIC ACCURACY OF CONTRAST ENHANCED COMPUTED TOMOGRAPHY IN STAGING OF COLORECTAL CARCINOMA
title_full_unstemmed DIAGNOSTIC ACCURACY OF CONTRAST ENHANCED COMPUTED TOMOGRAPHY IN STAGING OF COLORECTAL CARCINOMA
title_sort diagnostic accuracy of contrast enhanced computed tomography in staging of colorectal carcinoma
publisher Army Medical College Rawalpindi
publishDate 2018
url https://doaj.org/article/8cfabf75514a49cdaeec4be864f309e8
work_keys_str_mv AT nasirasultana diagnosticaccuracyofcontrastenhancedcomputedtomographyinstagingofcolorectalcarcinoma
AT sumayyakhan diagnosticaccuracyofcontrastenhancedcomputedtomographyinstagingofcolorectalcarcinoma
AT salahuddinbaloch diagnosticaccuracyofcontrastenhancedcomputedtomographyinstagingofcolorectalcarcinoma
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