Long range synchronization within the enteric nervous system underlies propulsion along the large intestine in mice

Nick Spencer et al. made simultaneous multi-site electrophysiological recordings with video imaging of colonic wall movements from ex vivo mouse colon, in order to correlate propulsion of content with underlying electrical signals from the smooth muscle. Their results demonstrate that excitatory and...

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Autores principales: Nick J. Spencer, Lee Travis, Lukasz Wiklendt, Marcello Costa, Timothy J. Hibberd, Simon J. Brookes, Phil Dinning, Hongzhen Hu, David A. Wattchow, Julian Sorensen
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Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/8d074c84cd8c46d598041d4005601ffc
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spelling oai:doaj.org-article:8d074c84cd8c46d598041d4005601ffc2021-12-02T18:50:46ZLong range synchronization within the enteric nervous system underlies propulsion along the large intestine in mice10.1038/s42003-021-02485-42399-3642https://doaj.org/article/8d074c84cd8c46d598041d4005601ffc2021-08-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02485-4https://doaj.org/toc/2399-3642Nick Spencer et al. made simultaneous multi-site electrophysiological recordings with video imaging of colonic wall movements from ex vivo mouse colon, in order to correlate propulsion of content with underlying electrical signals from the smooth muscle. Their results demonstrate that excitatory and inhibitory junction potentials are synchronized in both the proximal and distal colon, suggesting that the enteric nervous system network communicates over a longer range than previously expected.Nick J. SpencerLee TravisLukasz WiklendtMarcello CostaTimothy J. HibberdSimon J. BrookesPhil DinningHongzhen HuDavid A. WattchowJulian SorensenNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-17 (2021)
institution DOAJ
collection DOAJ
language EN
topic Biology (General)
QH301-705.5
spellingShingle Biology (General)
QH301-705.5
Nick J. Spencer
Lee Travis
Lukasz Wiklendt
Marcello Costa
Timothy J. Hibberd
Simon J. Brookes
Phil Dinning
Hongzhen Hu
David A. Wattchow
Julian Sorensen
Long range synchronization within the enteric nervous system underlies propulsion along the large intestine in mice
description Nick Spencer et al. made simultaneous multi-site electrophysiological recordings with video imaging of colonic wall movements from ex vivo mouse colon, in order to correlate propulsion of content with underlying electrical signals from the smooth muscle. Their results demonstrate that excitatory and inhibitory junction potentials are synchronized in both the proximal and distal colon, suggesting that the enteric nervous system network communicates over a longer range than previously expected.
format article
author Nick J. Spencer
Lee Travis
Lukasz Wiklendt
Marcello Costa
Timothy J. Hibberd
Simon J. Brookes
Phil Dinning
Hongzhen Hu
David A. Wattchow
Julian Sorensen
author_facet Nick J. Spencer
Lee Travis
Lukasz Wiklendt
Marcello Costa
Timothy J. Hibberd
Simon J. Brookes
Phil Dinning
Hongzhen Hu
David A. Wattchow
Julian Sorensen
author_sort Nick J. Spencer
title Long range synchronization within the enteric nervous system underlies propulsion along the large intestine in mice
title_short Long range synchronization within the enteric nervous system underlies propulsion along the large intestine in mice
title_full Long range synchronization within the enteric nervous system underlies propulsion along the large intestine in mice
title_fullStr Long range synchronization within the enteric nervous system underlies propulsion along the large intestine in mice
title_full_unstemmed Long range synchronization within the enteric nervous system underlies propulsion along the large intestine in mice
title_sort long range synchronization within the enteric nervous system underlies propulsion along the large intestine in mice
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/8d074c84cd8c46d598041d4005601ffc
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