Long range synchronization within the enteric nervous system underlies propulsion along the large intestine in mice
Nick Spencer et al. made simultaneous multi-site electrophysiological recordings with video imaging of colonic wall movements from ex vivo mouse colon, in order to correlate propulsion of content with underlying electrical signals from the smooth muscle. Their results demonstrate that excitatory and...
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Nature Portfolio
2021
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oai:doaj.org-article:8d074c84cd8c46d598041d4005601ffc2021-12-02T18:50:46ZLong range synchronization within the enteric nervous system underlies propulsion along the large intestine in mice10.1038/s42003-021-02485-42399-3642https://doaj.org/article/8d074c84cd8c46d598041d4005601ffc2021-08-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02485-4https://doaj.org/toc/2399-3642Nick Spencer et al. made simultaneous multi-site electrophysiological recordings with video imaging of colonic wall movements from ex vivo mouse colon, in order to correlate propulsion of content with underlying electrical signals from the smooth muscle. Their results demonstrate that excitatory and inhibitory junction potentials are synchronized in both the proximal and distal colon, suggesting that the enteric nervous system network communicates over a longer range than previously expected.Nick J. SpencerLee TravisLukasz WiklendtMarcello CostaTimothy J. HibberdSimon J. BrookesPhil DinningHongzhen HuDavid A. WattchowJulian SorensenNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-17 (2021) |
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Biology (General) QH301-705.5 |
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Biology (General) QH301-705.5 Nick J. Spencer Lee Travis Lukasz Wiklendt Marcello Costa Timothy J. Hibberd Simon J. Brookes Phil Dinning Hongzhen Hu David A. Wattchow Julian Sorensen Long range synchronization within the enteric nervous system underlies propulsion along the large intestine in mice |
description |
Nick Spencer et al. made simultaneous multi-site electrophysiological recordings with video imaging of colonic wall movements from ex vivo mouse colon, in order to correlate propulsion of content with underlying electrical signals from the smooth muscle. Their results demonstrate that excitatory and inhibitory junction potentials are synchronized in both the proximal and distal colon, suggesting that the enteric nervous system network communicates over a longer range than previously expected. |
format |
article |
author |
Nick J. Spencer Lee Travis Lukasz Wiklendt Marcello Costa Timothy J. Hibberd Simon J. Brookes Phil Dinning Hongzhen Hu David A. Wattchow Julian Sorensen |
author_facet |
Nick J. Spencer Lee Travis Lukasz Wiklendt Marcello Costa Timothy J. Hibberd Simon J. Brookes Phil Dinning Hongzhen Hu David A. Wattchow Julian Sorensen |
author_sort |
Nick J. Spencer |
title |
Long range synchronization within the enteric nervous system underlies propulsion along the large intestine in mice |
title_short |
Long range synchronization within the enteric nervous system underlies propulsion along the large intestine in mice |
title_full |
Long range synchronization within the enteric nervous system underlies propulsion along the large intestine in mice |
title_fullStr |
Long range synchronization within the enteric nervous system underlies propulsion along the large intestine in mice |
title_full_unstemmed |
Long range synchronization within the enteric nervous system underlies propulsion along the large intestine in mice |
title_sort |
long range synchronization within the enteric nervous system underlies propulsion along the large intestine in mice |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/8d074c84cd8c46d598041d4005601ffc |
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