3D microniches reveal the importance of cell size and shape
Little is known about how geometric cues affect cell function and gene expression in 3D settings. Here the authors use microniches of different geometries to control cell volume and shape, and by extension cell phenotype and lineage.
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Nature Portfolio
2017
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oai:doaj.org-article:8d0c0ce288684096b9d417fd6d474a1f2021-12-02T15:38:53Z3D microniches reveal the importance of cell size and shape10.1038/s41467-017-02163-22041-1723https://doaj.org/article/8d0c0ce288684096b9d417fd6d474a1f2017-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-02163-2https://doaj.org/toc/2041-1723Little is known about how geometric cues affect cell function and gene expression in 3D settings. Here the authors use microniches of different geometries to control cell volume and shape, and by extension cell phenotype and lineage.Min BaoJing XieAigars PiruskaWilhelm T. S. HuckNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-12 (2017) |
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Science Q |
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Science Q Min Bao Jing Xie Aigars Piruska Wilhelm T. S. Huck 3D microniches reveal the importance of cell size and shape |
description |
Little is known about how geometric cues affect cell function and gene expression in 3D settings. Here the authors use microniches of different geometries to control cell volume and shape, and by extension cell phenotype and lineage. |
format |
article |
author |
Min Bao Jing Xie Aigars Piruska Wilhelm T. S. Huck |
author_facet |
Min Bao Jing Xie Aigars Piruska Wilhelm T. S. Huck |
author_sort |
Min Bao |
title |
3D microniches reveal the importance of cell size and shape |
title_short |
3D microniches reveal the importance of cell size and shape |
title_full |
3D microniches reveal the importance of cell size and shape |
title_fullStr |
3D microniches reveal the importance of cell size and shape |
title_full_unstemmed |
3D microniches reveal the importance of cell size and shape |
title_sort |
3d microniches reveal the importance of cell size and shape |
publisher |
Nature Portfolio |
publishDate |
2017 |
url |
https://doaj.org/article/8d0c0ce288684096b9d417fd6d474a1f |
work_keys_str_mv |
AT minbao 3dmicronichesrevealtheimportanceofcellsizeandshape AT jingxie 3dmicronichesrevealtheimportanceofcellsizeandshape AT aigarspiruska 3dmicronichesrevealtheimportanceofcellsizeandshape AT wilhelmtshuck 3dmicronichesrevealtheimportanceofcellsizeandshape |
_version_ |
1718386060929531904 |