Comparative analysis of 1152 African-American and European-American men with prostate cancer identifies distinct genomic and immunological differences
Walter Rayford, Alp Tuna Beksac et al. investigated gene expression alterations in African-American and European-American men who underwent radical prostatectomy for prostate cancer. The observed differences include higher expression of inflammation genes and lower expression of mismatch repair gene...
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Nature Portfolio
2021
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oai:doaj.org-article:8d16165e890d4d0585cbc92f6aeacd1e2021-12-02T15:56:48ZComparative analysis of 1152 African-American and European-American men with prostate cancer identifies distinct genomic and immunological differences10.1038/s42003-021-02140-y2399-3642https://doaj.org/article/8d16165e890d4d0585cbc92f6aeacd1e2021-06-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02140-yhttps://doaj.org/toc/2399-3642Walter Rayford, Alp Tuna Beksac et al. investigated gene expression alterations in African-American and European-American men who underwent radical prostatectomy for prostate cancer. The observed differences include higher expression of inflammation genes and lower expression of mismatch repair genes in African-American men.Walter RayfordAlp Tuna BeksacJordan AlgerMohammed AlshalalfaMohsen AhmedIrtaza KhanUgo G. FalagarioYang LiuElai DavicioniDaniel E. SprattEdward M. SchaefferFelix Y. FengBrandon MahalPaul L. NguyenRobert B. DenMark D. GreenbergerRandy BradleyJustin M. WatsonMatthew BeamerLambros StamatakisDarrell J. CarmenShivanshu AwasthiJonathan HwangRachel WeilHarri MerisaariNihal MohamedLeslie A. DeaneDimple ChakravartyKamlesh K. YadavKosj YamoahSujit S. NairAshutosh K. TewariNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-9 (2021) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Biology (General) QH301-705.5 |
| spellingShingle |
Biology (General) QH301-705.5 Walter Rayford Alp Tuna Beksac Jordan Alger Mohammed Alshalalfa Mohsen Ahmed Irtaza Khan Ugo G. Falagario Yang Liu Elai Davicioni Daniel E. Spratt Edward M. Schaeffer Felix Y. Feng Brandon Mahal Paul L. Nguyen Robert B. Den Mark D. Greenberger Randy Bradley Justin M. Watson Matthew Beamer Lambros Stamatakis Darrell J. Carmen Shivanshu Awasthi Jonathan Hwang Rachel Weil Harri Merisaari Nihal Mohamed Leslie A. Deane Dimple Chakravarty Kamlesh K. Yadav Kosj Yamoah Sujit S. Nair Ashutosh K. Tewari Comparative analysis of 1152 African-American and European-American men with prostate cancer identifies distinct genomic and immunological differences |
| description |
Walter Rayford, Alp Tuna Beksac et al. investigated gene expression alterations in African-American and European-American men who underwent radical prostatectomy for prostate cancer. The observed differences include higher expression of inflammation genes and lower expression of mismatch repair genes in African-American men. |
| format |
article |
| author |
Walter Rayford Alp Tuna Beksac Jordan Alger Mohammed Alshalalfa Mohsen Ahmed Irtaza Khan Ugo G. Falagario Yang Liu Elai Davicioni Daniel E. Spratt Edward M. Schaeffer Felix Y. Feng Brandon Mahal Paul L. Nguyen Robert B. Den Mark D. Greenberger Randy Bradley Justin M. Watson Matthew Beamer Lambros Stamatakis Darrell J. Carmen Shivanshu Awasthi Jonathan Hwang Rachel Weil Harri Merisaari Nihal Mohamed Leslie A. Deane Dimple Chakravarty Kamlesh K. Yadav Kosj Yamoah Sujit S. Nair Ashutosh K. Tewari |
| author_facet |
Walter Rayford Alp Tuna Beksac Jordan Alger Mohammed Alshalalfa Mohsen Ahmed Irtaza Khan Ugo G. Falagario Yang Liu Elai Davicioni Daniel E. Spratt Edward M. Schaeffer Felix Y. Feng Brandon Mahal Paul L. Nguyen Robert B. Den Mark D. Greenberger Randy Bradley Justin M. Watson Matthew Beamer Lambros Stamatakis Darrell J. Carmen Shivanshu Awasthi Jonathan Hwang Rachel Weil Harri Merisaari Nihal Mohamed Leslie A. Deane Dimple Chakravarty Kamlesh K. Yadav Kosj Yamoah Sujit S. Nair Ashutosh K. Tewari |
| author_sort |
Walter Rayford |
| title |
Comparative analysis of 1152 African-American and European-American men with prostate cancer identifies distinct genomic and immunological differences |
| title_short |
Comparative analysis of 1152 African-American and European-American men with prostate cancer identifies distinct genomic and immunological differences |
| title_full |
Comparative analysis of 1152 African-American and European-American men with prostate cancer identifies distinct genomic and immunological differences |
| title_fullStr |
Comparative analysis of 1152 African-American and European-American men with prostate cancer identifies distinct genomic and immunological differences |
| title_full_unstemmed |
Comparative analysis of 1152 African-American and European-American men with prostate cancer identifies distinct genomic and immunological differences |
| title_sort |
comparative analysis of 1152 african-american and european-american men with prostate cancer identifies distinct genomic and immunological differences |
| publisher |
Nature Portfolio |
| publishDate |
2021 |
| url |
https://doaj.org/article/8d16165e890d4d0585cbc92f6aeacd1e |
| work_keys_str_mv |
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