Donepezil impairs memory in healthy older subjects: behavioural, EEG and simultaneous EEG/fMRI biomarkers.

Donepezil impairs memory in healthy older subjects: behavioural, EEG and simultaneous EEG/fMRI biomarkers.

Rising life expectancies coupled with an increasing awareness of age-related cognitive decline have led to the unwarranted use of psychopharmaceuticals, including acetylcholinesterase inhibitors (AChEIs), by significant numbers of healthy older individuals. This trend has developed despite very limi...

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Autores principales: Joshua H Balsters, Redmond G O'Connell, Mary P Martin, Alessandra Galli, Sarah M Cassidy, Sophia M Kilcullen, Sonja Delmonte, Sabina Brennan, Jim F Meaney, Andrew J Fagan, Arun L W Bokde, Neil Upton, Robert Lai, Marc Laruelle, Brian Lawlor, Ian H Robertson
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2011
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/8d255d00bd204b428334ae4868798300
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