Epigenetic differences at the HTR2A locus in progressive multiple sclerosis patients

Epigenetic differences at the HTR2A locus in progressive multiple sclerosis patients

Abstract The pathology of progressive multiple sclerosis (MS) is poorly understood. We have previously assessed DNA methylation in the CD4+ T cells of relapsing–remitting (RR) MS patients compared to healthy controls and identified differentially methylated regions (DMRs) in HLA-DRB1 and RNF39. This...

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Autores principales: Vicki E. Maltby, Rodney A. Lea, Sean Burnard, Alexandre Xavier, Thao Van Cao, Nicole White, Daniel Kennedy, Kira Groen, Katherine A. Sanders, Rebecca Seeto, Samara Bray, Melissa Gresle, Louise Laverick, Helmut Butzkueven, Rodney J. Scott, Jeannette Lechner-Scott
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/8d27ddf73fb74666a6a7c7b44026b9c1
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https://doaj.org/article/8d27ddf73fb74666a6a7c7b44026b9c1

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