Chromosome Aberrations Produced by Mestranol in Human Lymphocyte Cultures

In this investigation, the genotoxic properties of mestranol were examined in vitro. Human lymphocyte cultures were exposed for 72 h to mestranol at concentrations of 7.5, 15 and 30 µg/g. The genotoxic effects of the chemosterilant were assessed by numerical and structural chromosome aberrations.

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Autores principales: Teodorović Radislava, Drašković Vladimir, Đurić Spomenka, Nenadović Kartarina, Mirilović Milorad, Janković Ljiljana
Formato: article
Lenguaje:EN
Publicado: Sciendo 2019
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Acceso en línea:https://doaj.org/article/8d2d198791774e5e817c5a3fd1dd6bb5
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Sumario:In this investigation, the genotoxic properties of mestranol were examined in vitro. Human lymphocyte cultures were exposed for 72 h to mestranol at concentrations of 7.5, 15 and 30 µg/g. The genotoxic effects of the chemosterilant were assessed by numerical and structural chromosome aberrations.