Perturbed Wnt signaling leads to neuronal migration delay, altered interhemispheric connections and impaired social behavior

Functional consequence of transient delay in neuronal migration is unclear. This study shows that Wnt/C-Kit signaling regulates radial migration in rat somatosensory cortex, and that transient delay of L2/3 neuronal migration leads to interhemispheric connectivity alteration and abnormal social beha...

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Autores principales:	Riccardo Bocchi, Kristof Egervari, Laura Carol-Perdiguer, Beatrice Viale, Charles Quairiaux, Mathias De Roo, Michael Boitard, Suzanne Oskouie, Patrick Salmon, Jozsef Z. Kiss
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/8d2f9638ad8e4f4bba3636fccca2602d
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spelling	oai:doaj.org-article:8d2f9638ad8e4f4bba3636fccca2602d2021-12-02T14:42:01ZPerturbed Wnt signaling leads to neuronal migration delay, altered interhemispheric connections and impaired social behavior10.1038/s41467-017-01046-w2041-1723https://doaj.org/article/8d2f9638ad8e4f4bba3636fccca2602d2017-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01046-whttps://doaj.org/toc/2041-1723Functional consequence of transient delay in neuronal migration is unclear. This study shows that Wnt/C-Kit signaling regulates radial migration in rat somatosensory cortex, and that transient delay of L2/3 neuronal migration leads to interhemispheric connectivity alteration and abnormal social behavior.Riccardo BocchiKristof EgervariLaura Carol-PerdiguerBeatrice VialeCharles QuairiauxMathias De RooMichael BoitardSuzanne OskouiePatrick SalmonJozsef Z. KissNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Riccardo Bocchi Kristof Egervari Laura Carol-Perdiguer Beatrice Viale Charles Quairiaux Mathias De Roo Michael Boitard Suzanne Oskouie Patrick Salmon Jozsef Z. Kiss Perturbed Wnt signaling leads to neuronal migration delay, altered interhemispheric connections and impaired social behavior
description	Functional consequence of transient delay in neuronal migration is unclear. This study shows that Wnt/C-Kit signaling regulates radial migration in rat somatosensory cortex, and that transient delay of L2/3 neuronal migration leads to interhemispheric connectivity alteration and abnormal social behavior.
format	article
author	Riccardo Bocchi Kristof Egervari Laura Carol-Perdiguer Beatrice Viale Charles Quairiaux Mathias De Roo Michael Boitard Suzanne Oskouie Patrick Salmon Jozsef Z. Kiss
author_facet	Riccardo Bocchi Kristof Egervari Laura Carol-Perdiguer Beatrice Viale Charles Quairiaux Mathias De Roo Michael Boitard Suzanne Oskouie Patrick Salmon Jozsef Z. Kiss
author_sort	Riccardo Bocchi
title	Perturbed Wnt signaling leads to neuronal migration delay, altered interhemispheric connections and impaired social behavior
title_short	Perturbed Wnt signaling leads to neuronal migration delay, altered interhemispheric connections and impaired social behavior
title_full	Perturbed Wnt signaling leads to neuronal migration delay, altered interhemispheric connections and impaired social behavior
title_fullStr	Perturbed Wnt signaling leads to neuronal migration delay, altered interhemispheric connections and impaired social behavior
title_full_unstemmed	Perturbed Wnt signaling leads to neuronal migration delay, altered interhemispheric connections and impaired social behavior
title_sort	perturbed wnt signaling leads to neuronal migration delay, altered interhemispheric connections and impaired social behavior
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/8d2f9638ad8e4f4bba3636fccca2602d
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Perturbed Wnt signaling leads to neuronal migration delay, altered interhemispheric connections and impaired social behavior

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