Analysis of Choroidal Vascularity in Children with Unilateral Hyperopic Amblyopia

Abstract This institutional case control study was carried out to compare choroidal vascularity (CV) in amblyopic eyes, fellow eyes, and control eyes in children with unilateral hyperopic amblyopia. Sixty-four eyes of 32 childeren with unilateral anisometropic hyperopic amblyopia and 38 eyes of 19 h...

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Autores principales:	Jiwon Baek, Anna Lee, Miyoung Chu, Nam Yeo Kang
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/8d30c10cc30048119343ae1690a226bb
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spelling	oai:doaj.org-article:8d30c10cc30048119343ae1690a226bb2021-12-02T16:08:28ZAnalysis of Choroidal Vascularity in Children with Unilateral Hyperopic Amblyopia10.1038/s41598-019-48613-32045-2322https://doaj.org/article/8d30c10cc30048119343ae1690a226bb2019-08-01T00:00:00Zhttps://doi.org/10.1038/s41598-019-48613-3https://doaj.org/toc/2045-2322Abstract This institutional case control study was carried out to compare choroidal vascularity (CV) in amblyopic eyes, fellow eyes, and control eyes in children with unilateral hyperopic amblyopia. Sixty-four eyes of 32 childeren with unilateral anisometropic hyperopic amblyopia and 38 eyes of 19 healthy children (controls), aged 3 to 16 years. Subfoveal choroidal thickness (CT) and CV were measured using spectral domain optical coherence tomography. The mean subfoveal CT of amblyopic eyes (338.9 ± 60.0 μm) was greater than that of fellow eyes (315.3 ± 63.3 μm, P = 0.043) and control eyes (313.0 ± 42.1 μm, P = 0.025). The mean CV of amblyopic eyes (0.715 ± 0.020) was greater than that of control eyes (0.700 ± 0.020, P < 0.001). While a positive correlation between CT and CV was found in normal eyes (r = 0.470, P = 0.004), a strong negative correlation existed in amblyopic eyes (r = −0.684, P < 0.001). In conclusion, although mean CV was higher in amblyopic eyes, the negative correlation between CT and CV may suggests insufficient blood supply to the outer retina and choroid in the affected eyes of patients with unilateral anisometropic hyperopic amblyopia.Jiwon BaekAnna LeeMiyoung ChuNam Yeo KangNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 9, Iss 1, Pp 1-8 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Jiwon Baek Anna Lee Miyoung Chu Nam Yeo Kang Analysis of Choroidal Vascularity in Children with Unilateral Hyperopic Amblyopia
description	Abstract This institutional case control study was carried out to compare choroidal vascularity (CV) in amblyopic eyes, fellow eyes, and control eyes in children with unilateral hyperopic amblyopia. Sixty-four eyes of 32 childeren with unilateral anisometropic hyperopic amblyopia and 38 eyes of 19 healthy children (controls), aged 3 to 16 years. Subfoveal choroidal thickness (CT) and CV were measured using spectral domain optical coherence tomography. The mean subfoveal CT of amblyopic eyes (338.9 ± 60.0 μm) was greater than that of fellow eyes (315.3 ± 63.3 μm, P = 0.043) and control eyes (313.0 ± 42.1 μm, P = 0.025). The mean CV of amblyopic eyes (0.715 ± 0.020) was greater than that of control eyes (0.700 ± 0.020, P < 0.001). While a positive correlation between CT and CV was found in normal eyes (r = 0.470, P = 0.004), a strong negative correlation existed in amblyopic eyes (r = −0.684, P < 0.001). In conclusion, although mean CV was higher in amblyopic eyes, the negative correlation between CT and CV may suggests insufficient blood supply to the outer retina and choroid in the affected eyes of patients with unilateral anisometropic hyperopic amblyopia.
format	article
author	Jiwon Baek Anna Lee Miyoung Chu Nam Yeo Kang
author_facet	Jiwon Baek Anna Lee Miyoung Chu Nam Yeo Kang
author_sort	Jiwon Baek
title	Analysis of Choroidal Vascularity in Children with Unilateral Hyperopic Amblyopia
title_short	Analysis of Choroidal Vascularity in Children with Unilateral Hyperopic Amblyopia
title_full	Analysis of Choroidal Vascularity in Children with Unilateral Hyperopic Amblyopia
title_fullStr	Analysis of Choroidal Vascularity in Children with Unilateral Hyperopic Amblyopia
title_full_unstemmed	Analysis of Choroidal Vascularity in Children with Unilateral Hyperopic Amblyopia
title_sort	analysis of choroidal vascularity in children with unilateral hyperopic amblyopia
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/8d30c10cc30048119343ae1690a226bb
work_keys_str_mv	AT jiwonbaek analysisofchoroidalvascularityinchildrenwithunilateralhyperopicamblyopia AT annalee analysisofchoroidalvascularityinchildrenwithunilateralhyperopicamblyopia AT miyoungchu analysisofchoroidalvascularityinchildrenwithunilateralhyperopicamblyopia AT namyeokang analysisofchoroidalvascularityinchildrenwithunilateralhyperopicamblyopia
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Analysis of Choroidal Vascularity in Children with Unilateral Hyperopic Amblyopia

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